The state of the circulatory, respiratory and hemostasis organs of the servisemen, suffered from coronavirus pneumonia, in a remote recovery period

Abstract

The problem of the long-term effects of COVID-19, especially its severe forms, is already acutely relevant for world healthcare. Severe course of the novel coronavirus infection (“cytokine storm”) may be accompanied with the damage of respiratory system, circulatory system, and hemostasis.

In the Department of Hospital Therapy Military Medical Academy have been examined 64 servicemen: 1^st group of 44 people aged 46.1 ± 7 years with developed “cytokine storm”; 2^nd group — 20 men 47 ± 4.4 years without this complication. Patients were screened and treated under the standard scheme; 3 months after discharge from the hospital, respiratory, heart failure and D-dimer levels were assessed.

There was a significant increase pulmonary damage with decrease in saturation to 92.3 % (p = 0.003) in the 1^st group; laboratory signs of myocardial lesions: increase of troponin T to 15.4 ng/l (p = 0.001), a significant increase in the total creatine phosphokinase, aspartate amine transferase and alanine aminotransferase compared to patients of the 2^nd group. The average rates of standard hemogram, with the exception of platelet levels (173 × 10³/l, p = 0.03) in the 1^st group were no different from similar parameters of patients from the 2^nd group. It was drawn to attention the reliable increase in C-reactive protein, D-dimer and ferritin in men of the 1^st group. During the reexamination after 3 months more often diagnosed the phenomenon of respiratory and heart failure and hypercoagulation in patients from the 1^st group, which dictates the need for further dynamic monitoring of this category (1 figure, 2 tables, bibliography: 14 refs).

Keywords

cardiometabolic changes / COVID-19-associated coagulopathy / D-dimer / heart failure / novel coronavirus infection / respiratory function

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RIGHTS & PERMISSIONS

Serdyukov D.Y., Rodichev N.S., Tretyakovа A.A.