Domestic devices for molecular genetic analysis: developments of the IAP RAS and SINTOL LLC

Abstract

The set of domestic devices and reagent kits for molecular genetic analysis has been developed, which provides for all stages of the study, from the automated isolation of nucleic acids, their amplification with real-time detection to classical and genome-wide DNA sequencing. With the help of the created equipment and reagent kits, approaches for the specific indication of pathogens of a wide range of diseases have been successfully implemented. The high efficiency of the proposed approaches is shown by the example of detecting and analyzing the RNA of the pathogen SARS-CoV-2 in the fight against the COVID-19 coronavirus pandemic (7 figs, bibliography: 4 refs).

Keywords

automation / molecular genetic analysis / nucleic acid / sequencing

References

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[6] Severe acute respiratory syndrome coronavirus 2 isolate Wuhan-Hu-1, complete genome. Доступен по: https://www.ncbi.nlm.nih.gov/nuccore/NC_045512 (дата обращения 13.05.2021).

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RIGHTS & PERMISSIONS

Kurochkin V.E., Alekseev Y.I., Petrov D.G., Evstrapov A.A.