INFLUENCE OF SOLUTION COFFEIN TO WORKING MEMORY AND MOVEMENT ACTIVITY OF RATS

Abstract

There are researched the influence of solution sodium coffein-benzoat to working memory and movement activity of rats. Research is conducted using study methodic of animal spatial thinking “radial labyrinth” suggested by American scientist D. Olton in author modification. There are engaged 18 white rats. They explored radial labyrinth twice for 6 min: before and after injection of drug (400 mg of sodium coffein-benzoat with 10 min exposure). Received data evidence about statistic significant decrease of motor activity of rats.

Keywords

movement activity / working memory / radial labyrinth / coffein-benzoate sodium

References

[1] 1. Буреш, Я. Методики и основные эксперименты по изучению мозга и поведения / Я. Буреш, О. Буреш, Д.П. Хьюстон / Пер. с англ. - М.: Высш. шк., 1991. - 399 с.

[2] 2. Зорина, З.А. Элементарное мышление животных: Учебное пособие / З.А. Зорина, И.И. Полетаева. - М.: Аспект Пресс, 2002. - 320 с.

[3] 3. Толкач, П.Г. Экспериментальная оценка эффективности применения нейропептидов при остром отравлении оксидом углерода: автореф. дис. … канд. мед. наук / П.Г. Толкач. - СПб.: ВМедА, 2016. - 19 с.

[4] 4. Mahdi, S. Effect of chronic administration and withdrawal of caffeine on motor function, cognitive function, anxiety, and the social behavior of BLC57 mice / S. Mahdi [et al.] // International Journal of Health Sciences. - 2019. - №13(2). - P.10-16.

[5] 5. Duarte, J.M.N. Impact of caffeine consumption on type 2 diabetes-induced spatial memory impairment and neurochemical alteration in the hippocampus / J.M.N. Duarte [et al.] // Front Neurosci. - 2018. - №12. - P.1015.

RIGHTS & PERMISSIONS

Chukhno S.D., Lesova E.M.