ANEMIA AS A MARKER OF RHEUMATIC DISEASE ACTIVITY

A. S Lezina; M. M Toporkov

doi:10.17816/rmmar43348

Russian Military Medical Academy Reports ›› 2020, Vol. 39 ›› Issue (1-1S) :77 -81. DOI: 10.17816/rmmar43348

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ANEMIA AS A MARKER OF RHEUMATIC DISEASE ACTIVITY

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Abstract

Rheumatic diseases are often accompanied by changes in the blood system, including anemia. Anemia not only worsens the quality of life of patients, but also adversely affects the course of rheumatic disease. Therefore, the work has been studied assessed the degree of severity of anemia of rheumatic diseases, correlation between anemia and rheumatoid arthritis activity has been identified, and the effectiveness of basic anti-inflammatory therapy on anemia in patients was assessed rheumatoid arthritis. 99 patients diagnosed with non-differentiated arthritis aged 23 to 65 years were enrolled in the study. Among them were 79 women (79.8%), the average age was 52.3 ± 9.72 years, and 20 men (20.2%), the average age was 46 ± 19.6 years. All patients were tested for rheumatoid arthritis by DAS 28, hemograms, which included determination of hemoglobin concentration, erythrocytes, mean hemoglobin content in erythrocyte. 77 (77.7%) patients were examined in dynamics after 6 months with the same volume of clinical-laboratory methods. In the course of the study it is established that in rheumatoid arthritis, a sufficiently high degree of severity of anemia in the debut of the disease is detected. The higher the degree of disease activity, the higher the severity of anemia, including hypochromia. The application of the principles of "treatment before goal" with the appointment of adequate basic anti-inflammatory therapy allows achieving remission or low activity in more patients, which leads to a significant decrease in the frequency of occurrence of anemia syndrome.

Keywords

anemia / anemia of chronic disease / rheumatic disease / activity disease / rheumatoid arthritis / systemic lupus erythematosus

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A. S Lezina, M. M Toporkov. ANEMIA AS A MARKER OF RHEUMATIC DISEASE ACTIVITY. Russian Military Medical Academy Reports, 2020, 39(1-1S): 77-81 DOI:10.17816/rmmar43348

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