Modern aspects of infusion therapy: review

Abstract

The infusion therapy is a routine procedure of the nowadays perioperative period and critical patient treatment. But there are controversial questions about the quantity, quality, start and duration of infusion therapy, which are under discussion. Modern infusion therapy includes intravenous administration of crystalloid solutions and more rarely colloid solutions. The type, amount and rate of infusion fluid depends on the indication for infusion therapy and the specific requirements of the patient. Nowadays colloidal solutions have limited indications. Crystalloid solutions are used for infusion therapy of patients with hypovolemia or dehydration, correction of free water deficiency, correction of electrolyte disorders, replenishment of ongoing fluid losses and replacement for patients who unable to drink water orally. All patients should be monitored with combination of clinical parameters and laboratory tests. Therapeutic endpoints should be determined. The moment these endpoints are achieved fluid therapy should be appropriately de-escalated in order to avoid overhydration.

Keywords

infusion therapy / crystalloid solution / colloid solution / critical condition

References

[1] Rewa O, Bagshaw SM. Principles of Fluid Management. Crit Care Clin. 2015;31(4):785–801. doi: 10.1016/j.ccc.2015.06.012

[2] Rewa O., Bagshaw S.M. Principles of Fluid Management // Crit Care Clin. 2015. Vol. 31, N 4. P. 785–801. doi: 10.1016/j.ccc.2015.06.012

[3] Finfer S, Myburgh J, Bellomo R. Intravenous fluid therapy in critically ill adults. Nat Rev Nephrol. 2018;14(9):541–557. doi: 10.1038/s41581-018-0044-0

[4] Finfer S., Myburgh J., Bellomo R. Intravenous fluid therapy in critically ill adults // Nat Rev Nephrol. 2018. Vol. 14, N 9. P. 541–557. doi: 10.1038/s41581-018-0044-0

[5] Vincent JL, Ince C, Bakker J. Clinical review: Circulatory shock — an update: a tribute to Professor Max Harry Weil. Crit Care. 2012;16(6):239. doi: 10.1186/cc11510

[6] Vincent J-L., Ince C., Bakker J. Clinical review: Circulatory shock — an update: a tribute to Professor Max Harry Weil // Critical Care. 2012. Vol 16, N 6. doi: 10.1186/cc11510

[7] Woodcock TE, Woodcock TM. Revised Starling equation and the glycocalyx model of transvascular fluid exchange: an improved paradigm for prescribing intravenous fluid therapy. Br J Anaesth. 2012;108(3):384–394. doi: 10.1093/bja/aer515

[8] Woodcock T.E., Woodcock T.M. Revised Starling equation and the glycocalyx model of transvascular fluid exchange: an improved paradigm for prescribing intravenous fluid therapy // Br J Anaesth. 2012. Vol. 108, N 3. P. 384–394. doi: 10.1093/bja/aer444

[9] Sokologorskiy SV. Glycocalyx — birth of a new clinical paradigm. Russian Journal of Anaesthesiology and Reanimatology. 2018;(4):22-29. (In Russ.) doi: 10.17116/anaesthesiology201804122

[10] Сокологорский С.В. Гликокаликс — рождение новой клинической парадигмы // Анестезиология и реаниматология. 2018. № 4. С. 22–29. doi: 10.17116/anaesthesiology201804122

[11] Ince C, Mayeux PR, Nguyen T, et al. The endothelium in sepsis. Shock. 2016;45(3):259–270. doi: 10.1097/SHK.0000000000000473

[12] Ince C., Mayeux P.R., Nguyen T., et al. The endothelium in sepsis // Shock. 2016. Vol. 45, N 3. P. 259–270. doi: 10.1097/shk.0000000000000473

[13] Aksu U, Bezemer R, Yavuz B, et al. Balanced vs unbalanced crystalloid resuscitation in a near-fatal model of hemorrhagic shock and the effects on renal oxygenation, oxidative stress, and inflammation. Resuscitation. 2012;83(6):767–773. doi: 10.1016/j.resuscitation.2011.11.022

[14] Aksu U., Bezemer R., Yavuz B., et al. Balanced vs unbalanced crystalloid resuscitation in a near-fatal model of hemorrhagic shock and the effects on renal oxygenation, oxidative stress, and inflammation // Resuscitation. 2012. Vol. 83, N 6. P. 767–773. doi: 10.1016/j.resuscitation.2011.11.022

[15] Van Regenmortel N, Jorens PG, Malbrain ML. Fluid management before, during and after elective surgery. Curr Opin Crit Care. 2014;20(4):390–395. doi: 10.1097/MCC.0000000000000113

[16] Van Regenmortel N., Jorens P.G., Malbrain M.L. Fluid management before, during and after elective surgery // Curr Opin Crit Care. 2014. Vol. 20, N 4. P. 390–395. doi: 10.1097/MCC.0000000000000113

[17] Padhi S, Bullock I, Li L, et al. Intravenous fluid therapy for adults in hospital: summary of NICE guidance. BMJ. 2013;347:f7073. doi: 10.1136/bmj.f7073

[18] Padhi S., Bullock I., Li L., Stroud M. National Institute for Health and Care Excellence (NICE) Guideline Development Group. Intravenous fluid therapy for adults in hospital: summary of NICE guidance // BMJ. 2013. Vol. 347. P. f7624. doi: 10.1136/bmj.f7073

[19] Navarro LH, Bloomstone JA, Auler JO Jr, et al. Perioperative fluid therapy: a statement from the international Fluid Optimization Group. Perioperative Medicine. 2015;10(4):3. doi: 10.1186/s13741-015-0014-z

[20] Navarro L.H.C., Bloomstone J.A., Auler J.O.C.Jr., et al. Perioperative fluid therapy: a statement from the international Fluid Optimization Group // Perioperative Medicine. 2015. Vol. 10, N. 4. P. 3. doi: 10.1186/s13741-015-0014-z

[21] Langer T, Limuti R, Tommasino C, et al. Intravenous fluid therapy for hospitalized and critically ill children: rationale, available drugs and possible side effects. Anaesthesiol Intensive Ther. 2018;50(1): 49–58. doi: 10.5603/AIT.a2017.0058

[22] Langer T., Limuti R., Tommasino C., et al. Intravenous fluid therapy for hospitalized and critically ill children: rationale, available drugs and possible side effects // Anaesthesiol Intensive Ther. 2018. Vol. 50, N 1. P. 49–58. doi: 10.5603/ait.a2017.0058

[23] Malbrain MLNG, Van Regenmortel N, Saugel B, et al. Principles of fluid management and stewardship in septic shock: it is time to consider the four D’s and the four phases of fluid therapy. Ann Intensive Care. 2018;8(1):66. doi: 10.1186/s13613-018-0402-x

[24] Malbrain M.L.N.G., Van Regenmortel N., Saugel B., et al. Principles of fluid management and stewardship in septic shock: it is time to consider the four D’s and the four phases of fluid therapy // Ann Intensive Care. 2018. Vol. 8, N 1. P. 66. doi: 10.1186/s13613-018-0402-x

[25] Myburgh JA, Mythen MG. Resuscitation fluids. N Engl J Med. 2013;369(13):1243–1251. doi: 10.1056/NEJMra1208627

[26] Myburgh J.A., Mythen M.G. Resuscitation fluids // N Engl J Med. 2013. Vol 369, N 13. P. 1243–1251. doi: 10.1056/NEJMra1208627

[27] Van Regenmortel N, De Weerdt T, Van Craenenbroeck AH, et al. Effect of isotonic versus hypotonic maintenance fluid therapy on urine output, fluid balance, and electrolyte homeostasis: a crossover study in fasting adult volunteers. Br J Anaesth. 2017;118(6):892–900. doi: 10.1093/bja/aex118

[28] Van Regenmortel N., De Weerdt T., Van Craenenbroeck A.H., et al. Effect of isotonic versus hypotonic maintenance fluid therapy on urine output, fluid balance, and electrolyte homeostasis: a crossover study in fasting adult volunteers // Br J Anaesth. 2017. Vol. 118, N 6. P. 892–900. doi: 10.1093/bja/aex118

[29] Moritz ML, Ayus JC. Maintenance Intravenous Fluids in Acutely Ill Patients. N Engl J Med. 2015;373(14):1350–1360. doi: 10.1056/NEJMra1412877

[30] Moritz M.L., Ayus J.C. Maintenance Intravenous Fluids in Acutely Ill Patients // N Engl J Med. 2015. Vol. 373, N 14. P. 1350–1360. doi: 10.1056/nejmra1412877

[31] Van Regenmortel N, Verbrugghe W, Roelant E, et al. Maintenance fluid therapy and fluid creep impose more significant fluid, sodium, and chloride burdens than resuscitation fluids in critically ill patients: a retrospective study in a tertiary mixed ICU population. Intensive Care Med. 2018;44(4):409–417. doi: 10.1007/s00134-018-5147-3

[32] Van Regenmortel N., Verbrugghe W., Roelant E., et al. Maintenance fluid therapy and fluid creep impose more significant fluid, sodium, and chloride burdens than resuscitation fluids in critically ill patients: a retrospective study in a tertiary mixed ICU population // Intensive Care Med. 2018. Vol. 44, N 4. P. 409–417. doi: 10.1007/s00134-018-5147-3

[33] Marik PE, Linde–Zwirble WT, Bittner EA, et al. Fluid administration in severe sepsis and septic shock, patterns and outcomes: an analysis of a large national database. Intensive Care Med. 2017;43(5):625–632. doi: 10.1007/s00134-016-4675-y

[34] Marik P.E., Linde–Zwirble W.T., Bittner E.A., et al. Fluid administration in severe sepsis and septic shock, patterns and outcomes: an analysis of a large national database // Intensive Care Med. 2017. Vol. 43, N 5. P. 625–632. doi: 10.1007/s00134-016-4675-y

[35] Cordemans C, De Laet I, Van Regenmortel N, et al. Aiming for a negative fluid balance in patients with acute lung injury and increased intra-abdominal pressure: a pilot study looking at the effects of PAL-treatment. Ann Intensive Care. 2012;2(Suppl 1):S15. doi: 10.1186/2110-5820-2-S1-S15

[36] Cordemans C., De Laet I., Van Regenmortel N. Aiming for a negative fluid balance in patients with acute lung injury and increased intra-abdominal pressure: a pilot study looking at the effects of PAL-treatment // Ann Intensive Care. 2012. Vol 2, Suppl 1. P. S15. doi: 10.1186/2110-5820-2-S1-S15

[37] Vincent JL, De Backer D. Circulatory shock. N Engl J Med. 2013;369(18):1726-1734. doi: 10.1056/NEJMra1208943

[38] Vincent J-L., De Backer D. Circulatory Shock // N Engl J Med. 2013. Vol. 369, N 18. P. 1726–1734. doi: 10.1056/nejmra1208943

[39] Neymark MI, Zhukov AS. Improvement of preoperative infusion therapy in patients with acute large bowel obstruction. Russian Journal of Anaesthesiology and Reanimatology. 2022;(2):54–59. (In Russ.) doi: 10.17116/anaesthesiology202202154

[40] Неймарк М.И., Жуков А.С. Пути совершенствования инфузионной терапии в предоперационном периоде у пациентов с острой обтурационной толстокишечной непроходимостью // Анестезиология и реаниматология. 2022. № 2. C. 54–59. doi: 10.17116/anaesthesiology202202154

[41] Malbrain MLNG, Langer T, Annane D, et al. Intravenous fluid therapy in the perioperative and critical care setting: Executive summary of the International Fluid Academy (IFA). Ann Intensive Care. 2020;10(1):64. doi: 10.1186/s13613-020-00679-3

[42] Malbrain M.L.N.G., Langer T., Annane D., et al. Intravenous fluid therapy in the perioperative and critical care setting: Executive summary of the International Fluid Academy (IFA) // Ann. Intensive Care. 2020. Vol. 10, N 1. P. 64. doi: 10.1186/s13613-020-00679-3

[43] Cecconi M, Hofer C, Teboul JL, et al. Fluid challenges in intensive care: the FENICE study: A global inception cohort study. Intensive Care Med. 2015;41(9):1529–1537. doi: 10.1007/s00134-015-3850-x

[44] Cecconi M., Hofer C., Teboul J.L., et al. Fluid challenges in intensive care: the FENICE study: a global inception cohort study // Intensive Care Med. 2015. Vol. 41, N 9. P. 1529–1537. doi: 10.1186/s13613-020-00679-3

[45] Bennett VA, Vidouris A, Cecconi M. Effects of Fluids on the Macro- and Microcirculations. Crit Care. 2018;22(1):74. doi: 10.1186/s13054-018-1993-1

[46] Bennett V.A., Vidouris A., Cecconi M. Effects of fluids on the macro- and microcirculations // Crit Care. 2018. Vol. 22, N 1. P. 74. doi: 10.1186/s13054-018-1993-1

[47] Bobovnik SV, Gorobets ES, Zabolotskikh IB, et al. Perioperative fluid therapy in adults. Russian Journal of Anaesthesiology and Reanimatology. 2021;(4):17–33. (In Russ.) doi: 10.17116/anaesthesiology20210417

[48] Бобовник С.В., Горобец Е.С., Заболотских И.Б., и др. Периоперационная инфузионная терапия у взрослых. Анестезиология и реаниматология. 2021. № 4. С. 17–33. doi: 10.17116/anaesthesiology20210417

[49] Hansen PB, Jensen BL, Skott O. Chloride regulates afferent arteriolar contraction in response to depolarization. Hypertension. 1998;32(6):1066–1070. doi: 10.1161/01.hyp.32.6.1066

[50] Hansen P.B., Jensen B.L., Skott O. Chloride regulates afferent arteriolar contraction in response to depolarization // Hypertension. 1998. Vol. 32, N 6. P. 1066–1070. doi: 10.1161/01.hyp.32.6.1066

[51] Pfortmueller CA, Fleischmann E. Acetate-buffered crystalloid fluids: Current knowledge, a systematic review. J Crit Care. 2016;35:96–104. doi: 10.1016/j.jcrc.2016.05.006

[52] Pfortmueller C.A., Fleischmann E. Acetate-buffered crystalloid fluids: current knowledge, a systematic review // J Crit Care. 2016. Vol. 35. P. 96–104. doi: 10.1016/j.jcrc.2016.05.006

[53] Langer T, Santini A, Scotti E, et al. Intravenous balanced solutions: from physiology to clinical evidence. Anaesthesiol Intensive Ther. 2015;47 Spec No:s78–88. doi: 10.5603/AIT.a2015.0079

[54] Langer T., Santini A., Scotti E., et al. Intravenous balanced solutions: from physiology to clinical evidence // Anaesthesiol Intensive Ther. 2015. Vol. 47, Spec N. P. s78–88. doi: 10.5603/AIT.a2015.0079

[55] Langer T, Scotti E, Carlesso E, et al. Electrolyte shifts across the artificial lung in patients on extracorporeal membrane oxygenation: interdependence between partial pressure of carbon dioxide and strong ion difference. J Crit Care. 2015;30(1):2–6. doi: 10.1016/j.jcrc.2014.09.013

[56] Langer T., Scotti E., Carlesso E., et al. Electrolyte shifts across the artificial lung in patients on extracorporeal membrane oxygenation: interdependence between partial pressure of carbon dioxide and strong ion difference // J Crit Care. 2015. Vol. 30, N 1. P. 2–6. doi: 10.1016/j.jcrc.2014.09.013

[57] Morgan TJ, Venkatesh B, Hall J. Crystalloid strong ion difference determines metabolic acid-base change during in vitro hemodilution. Crit Care Med. 2002;30(1):157–160. doi: 10.1097/00003246-200201000-00022

[58] Morgan T.J., Venkatesh B., Hall J. Crystalloid strong ion difference determines metabolic acid–base change during in vitro hemodilution // Crit Care Med. 2002. Vol. 30, N 1. P. 157–160. doi: 10.1097/00003246-200201000-00022

[59] Ushkalova EA, Zyryanov SK, Zatolochina KE, Butranova OI. Infusion fluids: a clinical pharmacologist’s view. Russian Journal of Anaesthesiology and Reanimatology. 2021;(6):100–106. (In Russ) doi: 10.17116/anaesthesiology2021061100

[60] Ушкалова Е.А., Зырянов С.К., Затолочина К.Э., Бутранова О.И. Инфузионные растворы: взгляд клинического фармаколога //Анестезиология и реаниматология. 2021. № 6. С. 100–106. doi: 10.17116/anaesthesiology2021061100

[61] Kuca T, Butler MB, Erdogan M, Green RS. A comparison of balanced and unbalanced crystalloid solutions in surgery patient outcomes. Anaesth Crit Care Pain Med. 2017;36(6):371–376. doi: 10.1016/j.accpm.2016.10.001

[62] Kuca T., Butler M.B., Erdogan M., Green R.S. A comparison of balanced and unbalanced crystalloid solutions in surgery patient outcomes // Anaesth Crit Care Pain Med. 2017. Vol. 36, N 6. P. 371–376. doi: 10.1016/j.accpm.2016.10.001

[63] Koeppen BM, Stanton BA. Physiology of Body Fluids, Editor(s): Renal Physiology (5th Edition), Mosby, 2013.

[64] Koeppen B.M., Stanton B.A. Physiology of Body Fluids, Editor(s): Renal Physiology (5th Edition), Mosby, 2013.

[65] Zazzeron L, Gattinoni L, Caironi P. Role of albumin, starches and gelatins versus crystalloids in volume resuscitation of critically ill patients. Curr Opin Crit Care. 2016;22(5):428–436. doi: 10.1097/MCC.0000000000000341

[66] Zazzeron L., Gattinoni L., Caironi P. Role of albumin, starches and gelatins versus crystalloids in volume resuscitation of critically ill patients // Curr Opin Crit Care. 2016. Vol. 22, N 5, P. 428–36. doi: 10.1097/MCC.0000000000000341

[67] Caironi P, Tognoni G, Masson S, et al. Albumin replacement in patients with severe sepsis or septic shock. N Engl J Med. 2014;370(15):1412–1421. doi: 10.1056/NEJMoa1305727

[68] Caironi P., Tognoni G., Masson S., et al. Albumin replacement in patients with severe sepsis or septic shock // N Engl J Med. 2014. Vol. 370, N 15. P. 1412–1421. doi: 10.1056/NEJMoa1305727

[69] SAFE Study Investigators; Finfer S, McEvoy S, et al. Impact of albumin compared to saline on organ function and mortality of patients with severe sepsis. Intensive Care Med. 2011;37(1):86–96. doi: 10.1007/s00134-010-2039-6

[70] Investigators S.S., Finfer S., McEvoy S., et al. Impact of albumin compared to saline on organ function and mortality of patients with severe sepsis // Intensive Care Med. 2011. Vol. 37, N 1. P. 86–96. doi: 10.1007/s00134-010-2039-6

[71] Lewis SR, Pritchard MW, Evans DJ, et al. Colloids versus crystalloids for fluid resuscitation in critically ill people. Cochrane Database Syst Rev. 2018;8(8):CD000567. doi: 10.1002/14651858.CD000567.pub7

[72] Lewis S.R., Pritchard M.W., Evans D.J., et al. Colloids versus crystalloids for fluid resuscitation in critically ill people // Cochrane Database Syst Rev. 2018. N 8. P. CD000567. doi: 10.1002/14651858.CD000567.pub7

[73] Frenette AJ, Bouchard J, Bernier P, et al. Albumin administration is associated with acute kidney injury in cardiac surgery: a propensity score analysis. Crit Care. 2014;18(6):602. doi: 10.1186/s13054-014-0602-1

[74] Frenette A.J., Bouchard J., Bernier P., et al. Albumin administration is associated with acute kidney injury in cardiac surgery: a propensity score analysis // Crit Care. 2014. Vol. 18, N 6. P. 602. doi: 10.1186/s13054-014-0602-1

[75] Guidet B, Ghout I, Ropers J, Aegerter P. Economic model of albumin infusion in septic shock: The EMAISS study. Acta Anaesthesiol Scand. 2020;64(6):781–788. doi: 10.1111/aas.13559

[76] Guidet B., Ghout I., Ropers J., Aegerter P. Economic model of albumin infusion in septic shock: The EMAISS study // Acta Anaesthesiol Scand. 2020. Vol. 64, N 6. doi: 10.1111/aas.13559

[77] O’Malley CMN, Frumento RJ, Hardy MA, et al. A randomized, double-blind comparison of lactated Ringer’s solution and 0.9% NaCl during renal transplantation. Anesth Analg. 2005;100(5):1518–1524. doi: 10.1213/01.ANE.0000150939.28904.81

[78] O’Malley C.M.N., Frumento R.J., Hardy M.A., et al. A Randomized, Double-Blind Comparison of Lactated Ringer’s Solution and 0.9% NaCl During Renal Transplantation // Anesth Analg. 2005. Vol. 100, N 5. P. 1518–1524. doi: 10.1213/01.ane.0000150939.28904.81

[79] Khajavi MR, Etezadi F, Moharari RS, et al. Effects of normal saline vs. lactated ringer’s during renal transplantation. Ren Fail. 2008;30(5):535–539. doi: 10.1080/08860220802064770

[80] Khajavi M.R., Etezadi F., Moharari R.S., et al. Effects of Normal Saline vs. Lactated Ringer’s during Renal Transplantation // Ren Fail. 2008. Vol. 30, N 5. P. 535–539. doi: 10.1080/08860220802064770

[81] Raiman M, Mitchell CG, Biccard BM, Rodseth RN. Comparison of hydroxyethyl starch colloids with crystalloids for surgical patients: A systematic review and meta-analysis. Eur J Anaesthesiol. 2016;33(1):42–48. doi: 10.1097/EJA.0000000000000328

[82] Raiman M., Mitchell C.G., Biccard B.M., Rodseth R.N. Comparison of hydroxyethyl starch colloids with crystalloids for surgical patients: a systematic review and meta-analysis // Eur J Anaesthesiol. 2016. Vol. 33, N 1. P. 42–48. doi: 10.1097/EJA.0000000000000328

[83] Uz Z, Ince C, Guerci P, et al. Recruitment of sublingual microcirculation using handheld incident dark field imaging as a routine measurement tool during the postoperative de-escalation phase-a pilot study in post ICU cardiac surgery patients. Perioper Med (Lond). 2018;7:18. doi: 10.1186/s13741-018-0091-x

[84] Uz Z., Ince C., Guerci P., et al. Recruitment of sublingual microcirculation using handheld incident dark field imaging as a routine measurement tool during the postoperative de-escalation phase-a pilot study in post ICU cardiac surgery patients // Perioperat Med (Lond). 2018. Vol. 9, N 7. P. 18. doi: 10.1186/s13741-018-0091-x

[85] Jaber S, Paugam C, Futier E, et al. Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial. Lancet. 2018;392(10141):31–40. doi: 10.1016/S0140-6736(18)31080-8

[86] Jaber S., Paugam C., Futier E., et al. Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial // Lancet. 2018. Vol. 392, N 10141. P. 31–40. doi: 10.1016/s0140-6736(18)31080-8

[87] Babayants AV, Ignatenko OV, Zinina EP, Kaledina IV. Modern views on infusion of crystalloids in intensive care. Russian Journal of Anaesthesiology and Reanimatology. 2021;(5):49–53. (In Russ) doi: 10.17116/anaesthesiology202105149

[88] Бабаянц А.В., Игнатенко О.В., Зинина Е.П., Каледина И.В. Современные взгляды на инфузию кристаллоидов в интенсивной терапии // Анестезиология и реаниматология. 2021. № 5. С. 49–53. doi: 10.17116/anaesthesiology202105149

[89] Jung B, Rimmele T, Le Goff C, et al. Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy. A prospective, multiple-center study. Crit Care. 2011;15(5):R238. doi: 10.1186/cc10487

[90] Jung B., Rimmele T., Le Goff C., et al. Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy. a prospective, multiple-center study // Crit Care. 2011. Vol. 15, N 5. P. R238. doi: 10.1186/cc10487

[91] Brandstrup B, Tønnesen H, Beier–Holgersen R, et al. Effects of intravenous fluid restriction on postoperative complications: comparison of two perioperative fluid regimens: a randomized assessor-blinded multicenter trial. Ann Surg. 2003;238(5):641–648. doi: 10.1097/01.sla.0000094387.50865.23

[92] Brandstrup B., Tonnesen H., Beier–Holgersen R., et al. Effects of intravenous fluid restriction on postoperative complications: comparison of two perioperative fluid regimens: a randomized assessor-blinded multicenter trial // Ann Surg. 2003. Vol. 238, N 5. P. 641–648. doi: 10.1097/01.sla.0000094387.50865.23

[93] Thacker JK, Mountford WK, Ernst FR, et al. Perioperative Fluid Utilization Variability and Association With Outcomes: Considerations for Enhanced Recovery Efforts in Sample US Surgical Populations. Ann Surg. 2016;263(3):502–510. doi: 10.1097/SLA.0000000000001402

[94] Thacker J.K., Mountford W.K., Ernst F.R., et al. Perioperative fluid utilization variability and association with outcomes: considerations for enhanced recovery efforts in sample US surgical populations // Ann Surg. 2016. Vol. 263, N 3. P. 502–510. doi: 10.1097/SLA.0000000000001402

[95] Silva JM Jr, de Oliveira AM, Nogueira FA, et al. The effect of excess fluid balance on the mortality rate of surgical patients: a multicenter prospective study. Crit Care. 2013;17(6):R288. doi: 10.1186/cc13151

[96] Silva J.M. Jr., de Oliveira A.M., Nogueira F.A., et al. The effect of excess fluid balance on the mortality rate of surgical patients: a multicenter prospective study // Crit Care. 2013. Vol. 17, N 6. P. R288. doi: 10.1186/cc13151

[97] Pearse RM, Harrison DA, MacDonald N, et al. Effect of a perioperative, cardiac output-guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery: a randomized clinical trial and systematic review. JAMA. 2014;311(21):2181–2190. doi: 10.1001/jama.2014.5305

[98] Pearse R.M., Harrison D.A., MacDonald N., et al. Effect of a perioperative, cardiac output-guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery: a randomized clinical trial and systematic review // JAMA. 2014. Vol. 311, N 21. P. 2181–2190. doi: 10.1001/jama.2014.5305

[99] Gustafsson UO, Scott MJ, Hubner M, et al. Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018. World J Surg. 2019;43(3):659–695. doi: 10.1007/s00268-018-4844-y

[100] Gustafsson U.O., Scott M.J., Hubner M., et al. Guidelines for perioperative care in elective colorectal surgery: enhanced recovery after surgery (ERAS®) society recommendations: 2018 // World J Surg. 2019. Vol. 43, N 3. P. 659–695. doi: 10.1007/s00268-018-4844-y

[101] Phan TD, Uda Y, Peyton PJ, et al. Effect of fluid strategy on stroke volume, cardiac output, and fluid responsiveness in adult patients undergoing major abdominal surgery: a sub-study of the Restrictive versus Liberal Fluid Therapy in Major Abdominal Surgery (RELIEF) trial. Br J Anaesth. 2021;126(4):818–825. doi: 10.1016/j.bja.2021.01.011

[102] Phan T.D., Uda Y., Peyton P.J., et al. Effect of fluid strategy on stroke volume, cardiac output, and fluid responsiveness in adult patients undergoing major abdominal surgery: a sub-study of the Restrictive versus Liberal Fluid Therapy in Major Abdominal Surgery (RELIEF) trial // Br J Anaesth. 2021. Vol. 126, N 4. P. 818–825. doi: 10.1016/j.bja.2021.01.011

[103] Acheampong A, Vincent JL. A positive fluid balance is an independent prognostic factor in patients with sepsis. Crit Care. 2015;19(1):251. doi: 10.1186/s13054-015-0970-1

[104] Acheampong A., Vincent J-L. A positive fluid balance is an independent prognostic factor in patients with sepsis // Crit Care. 2015. Vol. 19, N 1. P. 251. doi: 10.1186/s13054-015-0970-1

[105] De Oliveira FS, Freitas FG, Ferreira EM, et al. Positive fluid balance as a prognostic factor for mortality and acute kidney injury in severe sepsis and septic shock. J Crit Care. 2015;30(1):97–101. doi: 10.1016/j.jcrc.2014.09.002

[106] De Oliveira F.S., Freitas F.G., Ferreira E.M., et al. Positive fluid balance as a prognostic factor for mortality and acute kidney injury in severe sepsis and septic shock // J Crit Care. 2015. Vol 30, N 1. P. 97–101. doi: 10.1016/j.jcrc.2014.09.002

[107] Silva JM Jr, de Oliveira AM, Nogueira FA, et al. The effect of excess fluid balance on the mortality rate of surgical patients: a multicenter prospective study. Crit Care. 2013;17(6):R288. doi: 10.1186/cc13151

[108] Silva J.M.Jr., de Oliveira A.M., Nogueira F.A., et al. The effect of excess fluid balance on the mortality rate of surgical patients: a multicenter prospective study // Crit Care. 2013. Vol. 17, N 6. P. R288. doi: 10.1186/cc13151

[109] Marik PE, Linde–Zwirble WT, Bittner EA, et al. Fluid administration in severe sepsis and septic shock, patterns and outcomes: an analysis of a large national database. Intensive Care Med. 2017;43(5):625–632. doi: 10.1007/s00134-016-4675-y

[110] Marik P.E., Linde-Zwirble W.T., Bittner E.A., et al. Fluid administration in severe sepsis and septic shock, patterns and outcomes: an analysis of a large national database // Intensive Care Med. 2017. Vol. 43, N 5. P. 625–632. doi: 10.1007/s00134-016-4675-y

[111] Cordemans C, De Laet I, Van Regenmortel N, et al. Fluid management in critically ill patients: the role of extravascular lung water, abdominal hypertension, capillary leak, and fluid balance. Ann Intensive Care. 2012;2(Suppl. 1):S1. doi: 10.1186/2110-5820-2-S1-S1

[112] Cordemans C., De Laet I., Van Regenmortel N., et al. Fluid management in critically ill patients: the role of extravascular lung water, abdominal hypertension, capillary leak, and fluid balance // Ann Intensive Care. 2012. Vol. 5, N 2 Suppl 1. P. S1. doi: 10.1186/2110-5820-2-S1-S1

[113] Cordemans C, De Laet I, Van Regenmortel N, et al. Aiming for a negative fluid balance in patients with acute lung injury and increased intra-abdominal pressure: a pilot study looking at the effects of PAL-treatment. Ann Intensive Care. 2012;2(Suppl. 1):S15. doi: 10.1186/2110-5820-2-S1-S15

[114] Cordemans C., De Laet I., Van Regenmortel N., et al. Aiming for a negative fluid balance in patients with acute lung injury and increased intra-abdominal pressure: a pilot study looking at the effects of PAL-treatment // Ann Intensive Care. 2012. Vol. 5, N 2 Suppl. 1. P. S15. doi: 10.1186/2110-5820-2-S1-S15

[115] Dabrowski W, Kotlinska-Hasiec E, Schneditz D, et al. Continuous veno-venous hemofiltration to adjust fluid volume excess in septic shock patients reduces intra-abdominal pressure. Clin Nephrol. 2014;82(1):41–50. doi: 10.5414/CN108015.

[116] Dabrowski W., Kotlinska-Hasiec E., Schneditz D., et al. Continuous veno-venous hemofiltration to adjust fluid volume excess in septic shock patients reduces intra-abdominal pressure // Clin Nephrol. 2014. Vol. 82, N 1. P. 41–50. doi: 10.5414/CN108015.

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