Nutritional support in the complex of medical rehabilitation at the stage of adjuvant radiation therapy of breast cancer
Inna S. Evstigneeva , Valeriia O. Kozyreva , Elena B. Kudryavtseva
Clinical nutrition and metabolism ›› 2023, Vol. 4 ›› Issue (3) : 140 -149.
Nutritional support in the complex of medical rehabilitation at the stage of adjuvant radiation therapy of breast cancer
BACKGROUND: Currently it is known that there exists the need for complex medical rehabilitation at the stage of adjuvant radiation treatment of breast cancer. However, data on the combined use of nutritional support and physical factors at this stage of oncological treatment are not available.
AIM: Evaluation of the effectiveness of specialized therapeutic and preventive nutrition in patients with malignant breast diseases and a history of polychemotherapy at the stage of adjuvant radiation therapy in complex medical rehabilitation using low-temperature plasma and general magnetic therapy.
MATERIALS AND METHODS: A prospective simple randomized study was conducted, which involved 60 patients at the stage of adjuvant radiation therapy for breast cancer. The main group (n=30) received a course of medical rehabilitation with the inclusion of nutritional support using specialized therapeutic and preventive nutrition LEOVIT ONCO®, as well as exposure to low-temperature plasma and general magnetotherapy. In the comparison group (n=30), the rehabilitation course included general magnetic therapy without therapeutic and preventive nutrition. All patients underwent individual physiotherapy exercises, and sessions with a medical psychologist. The results obtained were recorded using clinical and functional, laboratory, instrumental studies.
RESULTS: It has been established that the use of specialized dietary products LEOVIT ONCO and physical factors is an effective method of rehabilitation. The use of nutritional support demonstrates the maintenance of the patient’s protein status, reduces intoxication, and reduces the negative impact of oxidative stress factors in the body at the stage of adjuvant radiation treatment. The inclusion of low-temperature plasma and general magnetic therapy in the rehabilitation program has a beneficial effect on hemomicrocirculation in the area of ionizing radiation exposure.
CONCLUSION: The use of nutritional support and physical factors, as a component of complex medical rehabilitation, helps to maintain the optimal nutritional status of the patient, reduces the manifestations of skin radiation reactions, improves the psycho-emotional state of patients and the quality of life of patient.
medical rehabilitation / nutritional support / сold plasma / mammary cancer / radiation therapy
| [1] |
Presidential Decree No. 204 of May 7, 2018 “On National Goals and Strategic Objectives of the Development of the Russian Federation for the Period until 2024”. Available from: http://www.kremlin.ru/acts/bank/43027 Cited: 01 Jan 2023. (In Russ). |
| [2] |
Указ Президента РФ от 7 мая 2018 г. № 204 «О национальных целях и стратегических задачах развития Российской Федерации на период до 2024 года». Режим доступа: http://www.kremlin.ru/acts/bank/43027 Дата обращения: 01.01.2023 |
| [3] |
Roitberg GE, Tulkina EE, Doros ZV, et al. Organization of multidisciplinary rehabilitation of cancer patients. Bulletin of rehabilitation medicine. 2019;(5):14–20. EDN: BVRIPO |
| [4] |
Ройтберг Г.Е., Тюлькина Е.Е., Дорош Ж.В., и др. Организация мультидисциплинарной реабилитации пациентов онкологического профиля // Вестник восстановительной медицины. 2019. № 5. С. 14–20. EDN: BVRIPO |
| [5] |
Gameeva EV, Stepanova AM, Tkachenko GA, et al. Comprehensive rehabilitation of cancer patients: A review. Journal of Modern Oncology. 2022;24(1):90–96. EDN: UWXJQI doi: 10.26442/18151434.2022.1.201476 |
| [6] |
Гамеева Е.В., Степанова А.М., Ткаченко Г.А., и др. Комплексная реабилитация онкологических пациентов // Современная онкология. 2022. Т. 24, № 1. С. 90–96. EDN: UWXJQI doi: 10.26442/18151434.2022.1.201476 |
| [7] |
Doundoua DP, Staferov AV, Sorokin AV, Kedrova AG. Cardiooncology: chemotherapy drugs and radiation therapy impact on cardiovascular system. Clinical practice. 2016;(4):41–48. EDN: YLYKIZ |
| [8] |
Дундуа Д.П., Стаферов А.В., Сорокин А.В., Кедрова А.Г. Кардиоонкология: влияние химиотерапевтических препаратов и лучевой терапии на сердечно-сосудистую систему // Клиническая практика. 2016. № 4. С. 41–48. EDN: YLYKIZ |
| [9] |
Gameeva EV, Khoronenko VE, Shemetova MM. Nutritional insufficiency and therapy for cancer patients. Modern view on the problem. Siberian journal of oncology. 2020;19(2):116–124. EDN: JHKWYN doi: 10.21294/1814-4861-2020-19-2-116-124 |
| [10] |
Гамеева Е.В., Хороненко В.Э., Шеметова М.М. Нутритивная недостаточность и терапия онкологических пациентов. Современный взгляд на проблему // Сибирский онкологический журнал. 2020. Т. 19, № 2. С. 116–124. EDN: JHKWYN doi: 10.21294/1814-4861-2020-19-2-116-124 |
| [11] |
Gameeva EV, Stepanova AM, Kostin AA. Effects of nutritional support in cancer patients receiving chemotherapy. Head and Neck Tumors (HNT). 2021;11(4):50–57. EDN: HDJJTG doi: 10.17650/2222-1468-2021-11-4-50-57 |
| [12] |
Гамеева Е.В., Степанова А.М., Костин А.А. Эффекты нутритивной поддержки, проводимой при лекарственном противоопухолевом лечении пациентов онкологического профиля // Опухоли головы и шеи. 2021. Т. 11, № 4. С. 50–57. EDN: HDJJTG doi: 10.17650/2222-1468-2021-11-4-50-57 |
| [13] |
Nicol MJ, Brubaker TR, Honish BJ, et al. Antibacterial effects of low-temperature plasma generated by atmospheric-pressure plasma jet are mediated by reactive oxygen species. Sci Rep. 2020;10(1):30-66. doi: 10.1038/s41598-020-59652-6 |
| [14] |
Nicol M.J., Brubaker T.R., Honish B.J., et al. Antibacterial effects of low-temperature plasma generated by atmospheric-pressure plasma jet are mediated by reactive oxygen species // Sci Rep. 2020. Vol. 10, N 1. P. 30-66. doi: 10.1038/s41598-020-59652-6 |
| [15] |
Plattfaut I, Besser M, Severing AL, et al. Plasma medicine and wound management: Evaluation of the antibacterial efficacy of a medically certified cold atmospheric argon plasma jet. Int J Antimicrob Agents. 2021;57(5):106319. doi: 10.1016/j.ijantimicag.2021.106319 |
| [16] |
Plattfaut I., Besser M., Severing A.L., et al. Plasma medicine and wound management: Evaluation of the antibacterial efficacy of a medically certified cold atmospheric argon plasma jet // Int J Antimicrob Agents. 2021. Vol. 57, N 5. P. 106319. doi: 10.1016/j.ijantimicag.2021.106319 |
| [17] |
Evstigneeva IS, Kozyreva VO, Gerasimenko MY. Experience in the use of low-temperature plasma in the therapy of radiation reactions. Russian Journal of Physiotherapy, Balneology and Rehabilitation. 2021;20(6):559–566. EDN: AHSCCW doi: 10.17816/rjpbr108081 |
| [18] |
Евстигнеева И.С., Козырева В.О., Герасименко М.Ю. Опыт применения низкотемпературной плазмы в терапии лучевых реакций // Физиотерапия, бальнеология и реабилитация. 2021. Т. 20, № 6. С. 559–566. EDN: AHSCCW doi: 10.17816/rjpbr108081 |
| [19] |
Gerasimenko MIu, Evstigneeva IS, Zaytseva TN. Magnetotherapy in patient rehabilitation after radical mastectomy. Problems of Balneology, Physiotherapy and Exercise Therapy. 2020;97(2):36–44. EDN: LVXOKR doi: 10.17116/kurort20209702136 |
| [20] |
Герасименко М.Ю., Евстигнеева И.С., Зайцева Т.Н. Магнитотерапия в реабилитации пациенток после радикальной мастэктомии // Вопросы курортологии, физиотерапии и лечебной физической культуры. 2020. Т. 97, № 2. С. 36–44. EDN: LVXOKR doi: 10.17116/kurort20209702136 |
| [21] |
Kucherova TY, Vusik MV, Cheremisina OV. Physical factors and their role in oncology. Physical and rehabilitation medicine, medical rehabilitation. 2019;1(3):12–17. EDN: XHUITI doi: 10.36425/2658-6843-2019-3-12-17 |
| [22] |
Кучерова Т.Я., Вусик М.В., Черемисина О.В. Физические факторы и их роль в онкологии // Физическая и реабилитационная медицина, медицинская реабилитация. 2019. Т. 1, № 3. С. 12–17. EDN: XHUITI doi: 10.36425/2658-6843-2019-3-12-17 |
| [23] |
Bossola M. Nutritional interventionsin head and neck cancer patients undergoing chemoradiotherapy: a narrative review. Nutrients. 2015;7(1):265–276. doi: 10.3390/nu7010265 |
| [24] |
Bossola M. Nutritional interventionsin head and neck cancer patients undergoing chemoradiotherapy: a narrative review // Nutrients. 2015. Vol. 7, N 1. P. 265–276. doi: 10.3390/nu7010265 |
| [25] |
Ivanov DV, Tokareva SV. Selected issues in magnetotherapy (brief literature review). Journal of New Medical Technologies. 2021; 15(4):94–102. EDN: HYPCQW doi: 10.24412/2075-4094-2021-4-3-4 |
| [26] |
Иванов Д.В., Токарева С.В. Избранные вопросы магнитотерапии (краткий обзор литературы) // Вестник новых медицинских технологий. 2021. T. 15, № 4. С. 94–102. EDN: HYPCQW doi: 10.24412/2075-4094-2021-4-3-4 |
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