Clinical case of an acute toxic-allergic reaction due to single intake of methotrexate

Vadim I. Mazurov; Mikhail S. Shostak; Elena Yu. Kalinina; Victor V. Ripachev; Roman A. Bashkinov

doi:10.17816/mechnikov201911253-58

HERALD of North-Western State Medical University named after I.I. Mechnikov ›› 2019, Vol. 11 ›› Issue (2) :53 -58. DOI: 10.17816/mechnikov201911253-58

Case report

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Clinical case of an acute toxic-allergic reaction due to single intake of methotrexate

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North-Western State Medical University named after I.I. Mechnikov

head of the department of therapy, rheumatology, examination of temporary disability and the quality of medical care. E.E. Eichwald, w.s. RF, Academician of the Russian Academy of Sciences, MD Professor

assistant of the Department of Therapy, Rheumatology, Examination of Temporary Disability and Quality of Medical Care E.E. Eichwald

Associate Professor, Department of Pathological Anatomy, Ph.D.

Assistant of the Department of Therapy, Rheumatology, Examination of Temporary Disability and Quality of Medical Care E.E. Eichwald North-Western State Medical University named after I.I. Mechnikov

resident of the department of therapy, rheumatology, examination of temporary disability and the quality of medical care. E.E. Eichwald North-Western State Medical University named after I.I. Mechnikov

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Abstract

This is the case report of an acute allergic reaction in a patient with psoriatic arthritis due to a single intake of low-dose methotrexate. We review the presentation, laboratory tests and results of autopsy. The management of the disease and its outcome were analyzed according to current treatment recommendations for psoriatic arthritis.

Keywords

psoriasis / psoriatic arthritis / methotrexate / drug hypersensitivity

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Vadim I. Mazurov, Mikhail S. Shostak, Elena Yu. Kalinina, Victor V. Ripachev, Roman A. Bashkinov. Clinical case of an acute toxic-allergic reaction due to single intake of methotrexate. HERALD of North-Western State Medical University named after I.I. Mechnikov, 2019, 11(2): 53-58 DOI:10.17816/mechnikov201911253-58

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References

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[1]	Российские клинические рекомендации. Ревматология / под ред. Е.Л.Насонова. – М.: ГЭОТАР-Медиа, 2017. – 464 с.: 87-110.

[2]

Баткаева Н.В., Коротаева Т.В., Баткаев Э.А. Распространенность псориатического артрита и коморбидных заболеваний у больных тяжелым псориазом: данные ретроспективного анализа госпитальной когорты // Современная ревматология. -2017. – Т. 11. - №1. – С.19-22. Batkaeva NV, Korotaeva TV, Batkaev EA. Prevalence of psoriatic arthritis and comorbidities in patients with severe psoriasis: Data of a retrospective analysis of a hospital cohort. Sovremennaya Revmatologiya=Modern Rheumatology Journal. 2017;11(1):19–22..

[3]

Коротаева ТВ, Корсакова ЮЛ, Логинова ЕЮ и др. Псориатический артрит. Клинические рекомендации по диагностике и лечению // Современная ревматология. – 2018. – Т. 12. №2. – С.22–35. Korotaeva TV, Korsakova Yu.L., Loginova EYu, et al. Psoriatic arthritis. Clinical guidelines for diagnosis and treatment. Sovremennaya Revmatologiya=Modern Rheumatology Journal. 2018;12(2):22–35.

[4]

Angel Lanas, Maarten Boers, Javier Nuevo . Gastrointestinal events in at-risk patients starting non-steroidal anti-inflammatory drugs (NSAIDs) for rheumatic diseases: the EVIDENCE study of European routine practice. Annals Of The Rheumatic Diseases. 2015 Apr;74(4):675-681. doi: 10.1136/annrheumdis-2013-204155

[5]	Чамурлиева МН, Логинова ЕЮ, Коротаева ТВ. Выявляемость псориатического артрита у больных псориазом в дерматологической и ревматологической клинике. Современная ревматология. 2016;10(4):47–50.

[6]	Федеральные клинические рекомендации по ведению больных псориазом. Доступно по: https://www.ismos.ru/guidelines/doc/psoriaz.pdf. Ссылка активна на 03.02.2019

[7]	Laura C Coates, Philip S Helliwell. Methotrexate efficacy in the Tight Control in Psoriatic arthritis (TICOPA) study. J Rheumatol. 2016 Feb; 43(2): 356–361.

[8]	Jonathan West, Simon Ogston, and John Foerster. Safety and Efficacy of Methotrexate in Psoriasis: A Meta-Analysis of Published Trials. PLoS One. 2016; 11(5): e0153740. doi: [10.1371/journal.pone.0153740]

[9]	The PLOS ONE Staff. Correction: Safety and Efficacy of Methotrexate in Psoriasis: A Meta-Analysis of Published Trials. PLoS One. 2016; 11(7): e0158928. doi: [10.1371/journal.pone.0158928]