Clinical case of Whipple’s disease

Marina F. Osipenko , Aleksandr P. Nadeev , Yuliya Yu. Venzhina , Elena A. Zhuk

HERALD of North-Western State Medical University named after I.I. Mechnikov ›› 2022, Vol. 14 ›› Issue (2) : 101 -108.

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HERALD of North-Western State Medical University named after I.I. Mechnikov ›› 2022, Vol. 14 ›› Issue (2) :101 -108. DOI: 10.17816/mechnikov105632
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Clinical case of Whipple’s disease

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Abstract

The article presents a clinical case of 68-years old patient with a Whipple’s disease. The diagnosis was made after 10 years of following-up in presence of gastroenterological symptoms. On examination flattened rounded villi with the content of PAS-positive (PAS — periodic acid Schiff) foamy macrophages, highly specific for Whipple’s disease, have been described in the biopsy specimen of the distal duodenum. The therapy led to a distinct positive dynamics persisting for 1 year.

Keywords

Whipple’s disease / PAS-positive macrophages / clinical case

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Marina F. Osipenko, Aleksandr P. Nadeev, Yuliya Yu. Venzhina, Elena A. Zhuk. Clinical case of Whipple’s disease. HERALD of North-Western State Medical University named after I.I. Mechnikov, 2022, 14(2): 101-108 DOI:10.17816/mechnikov105632

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Osipenko M.F., Nadeev A.P., Venzhina Y.Y., Zhuk E.A.

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