THE ROLE OF ANTI-MULLERIAN HORMONE IN THE PATOGENESIS OF ENDOMETRIOSIS
N. B Paramonova , Tatyana A. Semeryuk
V.F.Snegirev Archives of Obstetrics and Gynecology ›› 2019, Vol. 6 ›› Issue (4) : 193 -197.
THE ROLE OF ANTI-MULLERIAN HORMONE IN THE PATOGENESIS OF ENDOMETRIOSIS
Anti-Müllerian hormone is one of the most significant factors regulating woman’s reproductive function, which inhibits endogenous production of estrogens, induces cell cycle arrest, apoptosis and autophagy in human endometrial stromal cells. Disturbance of Anti-Müllerian hormone expression could be an important link to pathogenesis of endometriosis.
CYP19 / endometriosis / Anti-Müllerian hormone / receptors of Anti-Müllerian hormone / autophagy / apoptosis / CYP19
| [1] |
Signorile P., Baldi A. New evidence in endometriosis. Int. J. Biochem. Cell Biol. 2015; 60:19-22. doi:10.1016/j.biocel.2014.12.019 |
| [2] |
Hickey M., Ballard K., Farquhar C. Endometriosis. BMJ. 2014; 348(mar19 5): g1752-g1752. doi:10.1136/bmj.g1752 |
| [3] |
Krawczyk N., Banys-Paluchowski M., Schmidt D., Ulrich U., Fehm T. Endometriosis-associated Malignancy. Geburtshilfe Frauenheilkd. 2016; 76(02):176-81. doi:10.1055/s-0035-1558239 |
| [4] |
Romero I., Bast R. Minireview: Human ovarian cancer: biology, current management, and paths to personalizing therapy. Endocrinology. 2012;153(4):1593-602. doi:10.1210/en.2011-2123 |
| [5] |
Pollacco J., Sacco K., Portelli M., Schembri-Wismayer P., Calleja-Agius J. Molecular links between endometriosis and cancer. Gynecol. Endocrinol. 2012; 28(8): 577-81. doi:10.3109/09513590.2011.650761 |
| [6] |
Czyzyk A., Podfigurna A., Szeliga A., Meczekalski B. Update on endometriosis pathogenesis. Minerva Ginecol. 2017; 69(5): 447-61. doi:10.23736/S0026-4784.17.04048-5 |
| [7] |
Namkung J., Song J., Jo H. et al. Müllerian inhibiting substance induces apoptosis of human endometrial stromal cells in endometriosis. J. Clin. Endocrinol. Metab. 2012; 97(9): 3224-30. doi:10.1210/jc.2012-1538 |
| [8] |
Signorile P., Petraglia F., Baldi A. Anti-mullerian hormone is expressed by endometriosis tissues and induces cell cycle arrest and apoptosis in endometriosis cells. J. Experim. Clin. Cancer Res. 2014; 33(1). doi:10.1186/1756-9966-33-46 |
| [9] |
Kim S., Moon H., Lee M. et al. The expression of Müllerian inhibiting substance/anti-Müllerian hormone type II receptor in myoma and adenomyosis. Obstet. Gynecol. Sci. 2018; 61(1):127. doi:10.5468/ogs.2018.61.1.127 |
| [10] |
Ozzola G. Anti-Müllerian hormone: A brief review of the literature. Clin. Ter. 2017; 168(1): e14-e22. doi: 10.7417/CT.2017.1976 |
| [11] |
Kim J., MacLaughlin D., Donahoe P. Müllerian inhibiting substance/anti-Müllerian hormone: A novel treatment for gynecologic tumors. Obstet. Gynecol. Sci. 2014; 57(5): 343. doi:10.5468/ogs.2014.57.5.343 |
| [12] |
Wang J., Dicken C., Lustbader J., Tortoriello D. Evidence for a Müllerian-inhibiting substance autocrine/paracrine system in adult human endometrium. Fertil. Steril. 2009; 91(4):1195-203. doi:10.1016/j.fertnstert.2008.01.028 |
| [13] |
Carrarelli P., Rocha A., Belmonte G. et al. Increased expression of antimüllerian hormone and its receptor in endometriosis. Fertil. Steril. 2014;101(5):1353-8. doi:10.1016/j.fertnstert.2014.01.052 |
| [14] |
Gupta D., Hull M., Fraser I. et al. Endometrial biomarkers for the non-invasive diagnosis of endometriosis. Cochrane Database of Systematic Reviews. 2016. doi:10.1002/14651858.cd012165 |
| [15] |
Zhan L., Li J., Wei B. Autophagy in endometriosis: Friend or foe? Biochem. Biophys. Res. Commun. 2018; 495(1): 60-63. doi:10.1016/j.bbrc.2017.10.145 |
| [16] |
Grossman M., Nakajima S., Fallat M., Siow Y. Müllerian-inhibiting substance inhibits cytochrome P450 aromatase activity in human granulosa lutein cell culture. Fertil. Steril. 2008; 89(5):1364-70. doi:10.1016/j.fertnstert.2007.03.066 |
| [17] |
Yang H., Mei J., Chang K., Zhou W., Huang L., Li M. Autophagy in endometriosis. Am. J. Transl. Res. 2017; 9(11): 4707-25. PMCID: PMC5714760 |
| [18] |
Zhang L., Liu Y., Xu Y., Wu H., Wei Z., Cao Y. The expression of the autophagy gene beclin-1 mRNA and protein in ectopic and eutopic endometrium of patients with endometriosis. Int. J. Fertil. Steril. 2015; 8(4): 429-36. PMCID: PMC4355304 |
| [19] |
Choi J., Jo M., Lee E., Oh Y., Choi D. The role of autophagy in human endometrium. Biol. Reprod. 2012; 86(3). doi:10.1095/biolreprod.111.096206 1. |
| [20] |
Ruiz A., Rockfield S., Taran N. et al. Effect of hydroxychloroquine and characterization of autophagy in a mouse model of endometriosis. Cell Death and Disease. 2016; 7(1): e2059. doi:10.1038/cddis.2015.361 |
| [21] |
Sui X., Li Y., Sun Y., Li C., Li X., Zhang G. Expression and significance of autophagy genes LC3, Beclin1 and MMP-2 in endometriosis. Exp. Ther. Med. 2018;16(3):1958-62. doi:10.3892/etm.2018.6362 |
| [22] |
Mei J., Zhu X., Jin L., Duan Z., Li D., Li M. Estrogen promotes the survival of human secretory phase endometrial stromal cells via CXCL12/CXCR4 up-regulation-mediated autophagy inhibition. Hum. Reprod. 2015; 30(7): 1677-89. doi:10.1093/humrep/dev100 |
| [23] |
Borahay M., Lu F., Ozpolat B. et al. Mullerian inhibiting substance suppresses proliferation and induces apoptosis and autophagy in endometriosis cells in vitro. ISRN Obstet. Gynecol. 2013; 2013:1-6. doi:10.1155/2013/361489 |
| [24] |
Адамян Л.В., Асатурова А.В., Степанян А.А., Попрядухин А.Ю. Роль механизмов аноикиса и аутофагии в патогенезе эндометриоза (обзор литературы). Проблемы репродукции. 2017; 4: 81-6. / Adamyan L.V., Asaturova A.V., Stepanyan A.A., Popryaduhin A.Yu. The role of the mechanisms of anoikis and autophagy in the pathogenesis of endometriosis (a review). Prob. reprod. 2017; 4: 81-6 (in Russian) |
| [25] |
Choi J., Jo M., Lee E., Lee D, Choi D. Dienogest enhances autophagy induction in endometriotic cells by impairing activation of AKT, ERK1/2, and MTOR. Fertil. Steril. 2015; 104(3): 655-64.e1. doi: 10.1016/j.fertnstert.2015.05.020. |
| [26] |
Choi J., Jo M., Lee E., Kim H., Choi D. Differential induction of autophagy by mTOR is associated with abnormal apoptosis in ovarian endometriotic cysts. Mol. Hum. Reprod. 2013; 20(4):309-317. doi:10.1093/molehr/gat091 |
| [27] |
Pacchiarotti A., Frati P., Milazzo G., Catalano A., Gentile V., Moscarini M. Evaluation of serum anti-Mullerian hormone levels to assess the ovarian reserve in women with severe endometriosis. European J. Obstet. Gynecol. Reprod. Biol. 2014; 172: 62-4. doi:10.1016/j.ejogrb.2013.10.003 |
Eco-Vector
/
| 〈 |
|
〉 |