Contribution of genital mycoplasmas (Ureaplasmaparvum, Ureaplasma urealyticum, Mycoplasma hominis, Mycoplasma genitalium) to the development of pregnancy, labor, and postpartum period complications

Abstract

Prospective analysis of the course of pregnancy, labor, and postpartum period was carried out in 677 women screened for vulvovaginal and cervical infections and the course of the early neonatal period in their newborns was analyzed. Genital mycoplasmas were detected in the vagina and cervical canal in 304 (44.9%) patients: Ureaplasma parvum in 40.2%, U. urealyticum in 7.1%, Mycoplasma hominis in 4.6%, and M. genitalium in 0.6%. Genital mycoplasmas in the lower genital tract were combined with other opportunistic infections in the overwhelming majority of patients - in 232 (76.3%). Monocultures or combinations with only Lactobacillus spp. were isolated in just 72 (10.6%) cases. Colonization of the lower genital tract ofpregnant patients by opportunistic micro-organisms was an important risk factor for preterm delivery, preterm amniorrhea, delivery of small-for-date (<2500 g) babies, for postpartum endometritis and wound infection. On the other hand, it was obvious that genital mycoplasmoses were inessential for the pathogenesis of unfavorable outcomes ofpregnancy, labor, and postpartum period in women and of the early neonatal period in newborns.

Keywords

genital mycoplasmas / preterm delivery / preterm amniorrhea / postpartum pyoseptic complications

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