The role of magnesium in the treatment of premenstrual syndrome

Abstract

65 patients with premenstrual syndrome (PMS) participated in a clinical, laboratory, and instrumental study that included determining the level of magnesium in the blood serum, two groups of them were formed. All subjects received symptomatic therapy for PMS, but the patients of group 1 (32 people) were prescribed magnesium citrate with vitamin B₂ (Riboflavin) orally for 2 months, and patients of the 2nd group (33 people) — only vitamin B₂. In group 1 patients, the number of PMS symptoms significantly decreased. Patients of the 2nd group, after ineffective treatment with vitamin B₂, were additionally prescribed magnesium citrate after 2 months, which led to a positive effect. As a result of treatment with magnesium citrate with vitamin B₂, the frequency of symptoms such as anxiety, depression, resentment, tearfulness, and headache significantly decreased. The decrease in the frequency of other PMS symptoms was not statistically significant. There were no significant changes in the level of magnesium concentration in the blood serum.

Keywords

premenstrual syndrome / magnesium deficiency / magnesium citrate / vitamin B2 (Riboflavin)

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