The dynamics of somatosensory evoked potentials in patients with spinal cord injury treated by autologous haematopoietic stem cells

Abstract

The aim of this study was neurophysiologic estimation of ceil restorative therapy influence on afferent pathways of the injured spinal cord. The dynamic somatosensory evoked potentials studies were performed in chronic spinal cord injury patients treated by repeated transplantations of autologous haematopoietic stem cells. The data analysis revealed three stable effects of stem cells: 1) restoration of early cortical components of SEP: 2) Increase of early potentials amplitude; 3) Decrease of early potentials latency. No signs of worsening of spinal pathways function were revealed in any of the patients. The obtained data indicate on the restoration of nerve fibers, constituting the proprioceptive pathways of spinal cord.

Keywords

spinal cord / haematopoietic stem cells / somatosensory evoked potentials / proprioception

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