Infection of umbilical cord blood and embryos at early terms of gestation and embrionic hemopoiesis in the fetal liver

Abstract

Polymerase Chain Reaction method was used to check 180 samples of placenta, maternal and umbilical cord blood. Cytomegalovirus was detected: in placenta - 7,2%, no virus was detected in umbilical cord blood of newborn. Also, no EBV was detected in umbilical cord blood, but was detected in maternal blood and placenta (3,6%). RNA of hepatitis C virus was detected in 3,6% of umbilical cord blood and 5,4% of maternal blood and placenta. Total amount of infected samples for umbilical cord blood was 5,4%, for placentas - 20%. In anamnesis of women in childbirth, there was no data on presence of such infectious diseases.

Research of abortive embryos revealed the following: the most extensive infection is mycoplasma (17%), the pathogen is detected on 6 to 12 week of intrauterine development in tissues of liver, kidneys, heart, brain, and haematopoetic cells of embryos. 5% of embryos are affected by chlamydia, 6% - by ureaplasma, 4%-by hepatitis C, 2,5% - by EBV, there's plenty of mixed infections. 47% of embryos were affected by various types of infections, which could be detected as early as 6-10 week of development. The study of cellular composition of populace of haemopoetic cages, abstracted from the embryonic liver of garden-stuffs 7-12 weeks of gestation and his change is set at appearance of infections is conducted. We studied haemopoiesis in the liver taken from embryos between the 6th and 12th weeks of gestation staggered the different types of infections.

Keywords

umbilical cord blood / embryos / viral and urogenital infections

References

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