Tissue-engineered construction made of adipose derived multipotent mesenchymal stromal cells, polylactide scaffolds and platelet gel

T. B Buharova , A. V Volkov , E. N Antonov , E. B Vihrova , A. V Popova , V. K Popov , D. V Goldstein

Genes & Cells ›› 2013, Vol. 8 ›› Issue (4) : 61 -68.

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Genes & Cells ›› 2013, Vol. 8 ›› Issue (4) : 61 -68. DOI: 10.23868/gc121615
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Tissue-engineered construction made of adipose derived multipotent mesenchymal stromal cells, polylactide scaffolds and platelet gel

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Abstract

We have shown the efficacy of tissue-engineered construction made of adipose derived multipotent mesenchymal stromal cells predifferentiated in the osteogenic direction, polylactide scaffolds fabricated by surface selective laser sintering, and platelet gel for bone tissue regeneration on the heterotopic osteogenesis model in rats.

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tissue-engineered constructions / adipose derived multipotent mesenchymal stromal cells / polylactide scaffolds / platelet gel / heterotopic osteogenesis

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T. B Buharova, A. V Volkov, E. N Antonov, E. B Vihrova, A. V Popova, V. K Popov, D. V Goldstein. Tissue-engineered construction made of adipose derived multipotent mesenchymal stromal cells, polylactide scaffolds and platelet gel. Genes & Cells, 2013, 8(4): 61-68 DOI:10.23868/gc121615

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References

[1]

Деев Р.В., Исаев А.А., Кочиш А.Ю. и др. Клеточные технологии в травматологии и ортопедии: пути развития. Клеточная трансплантология и тканевая инженерия 2007; IIC4): 18-30.

[2]

Howard D., Buttery L.D., Shakesheff K.M. et al. Tissue engineering: strategies, stem cells and scaffolds. J. Anat. 2008; 213(1): 66-72.

[3]

Zuk P.A., Zhu M., Ashjian P. et al. Human adipose tissue is a source of multipotent stem cells. Mol. Biol. Cell. 2002; 13(12): 4279-95.

[4]

Lee J.A., Parrett B.M., Conejero J.A. et al. Biological alchemy: engineering bone and fat from fat-derived stem cells. Ann. Plast. Surg. 2003; 50(6): 610-7.

[5]

Jurgens W.J., Oedayrajsingh-Varma M.J., Helder M.N. et al. Effect of tissue-harvesting site on yield of stem cells derived from adipose tissue: implications for cell-based therapies. Cell Tissue Res. 2008; 332(3): 415-26.

[6]

Kilroy G.E., Foster S.J., Wu X. et al. Cytokine profile of human adipose-derived stem cells: expression of angiogenic, hematopoietic, and pro-inflammatory factors. J. Cell. Physiol. 2007; 212(3): 702-9.

[7]

Liu Y., Wang L., Kikuiri T. et al. Mesenchymal stem cell-based tissue regeneration is governed by recipient T lymphocytes via IFN-gamma and TNF-alpha. Nat. Med. 2011; 17: 1594-601.

[8]

Antonov E.N., Bagratashvili V.N., Howdle S.M. et al. Fabrication of polymer scaffolds for tissue engineering using surface selective laser sintering. Laser Physics 2006; 16: 774-87.

[9]

Conejero J.A., Lee J.A., Parrett B.M. Repair of palatal bone defects using osteogenically differentiated fat-derived stem cells. Plast. Reconstr. Surg. 2006; 117(3): 857-63.

[10]

Yoon E., Dhar S., Chun D.E. et al. In vivo osteogenic potential of human adipose-derived stem cells/poly lactide-co-glycolic acid constructs for bone regeneration in a rat critical-sized calvarial defect model. Tissue Eng. 2007; 13(3): 619-27.

[11]

Niemeyer Ph., Fechner K., Milz S. et al. Comparison of mesenchymal stem cells from bone marrow and adipose tissue for bone regeneration in a critical size defect of the sheep tibia and the influence of platelet-rich plasma. Biomaterials 2010; 31(13): 3572-9.

[12]

Логовская Л.В., Бухарова Т.Б., Волков А.В. и др. Индукция остеогенной дифференцировки мультипотентных мезенхимальных стромальных клеток жировой ткани человека. Клеточные технологии в биологии и медицине 2013; 1: 28-34.

[13]

Marx RE. Platelet-rich plasma: evidence to support its use. J. Oral. Maxillofac. Surg. 2004; 62(4): 489-96.

[14]

Бухарова Т.Б., Арутюнян И.В., Шустров С.А. и др. Тканеинженерная конструкция на основе мультипотентных стромальных клеток жировой ткани и материала «Остеоматрикс» для регенерации костной ткани. Клеточные технологии в биологии и медицине 2011; 3: 167-173.

[15]

Alsousou J., ThompsonM., HulleyP. et al. The biology of platelet-rich plasma and its application in trauma and orthopaedic surgery. J. Bone Joint Surg. Br. 2009; 91(8): 987-96.

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