Characteristics of neoosteogenesis in the model of critical defect of rats' parietal bone using traditional and three-dimensional morphometry

A. V Vasilyev , A. V Volkov , G. B Bolshakova , D. V Goldstein

Genes & Cells ›› 2014, Vol. 9 ›› Issue (4) : 121 -127.

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Genes & Cells ›› 2014, Vol. 9 ›› Issue (4) : 121 -127. DOI: 10.23868/gc120414
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Characteristics of neoosteogenesis in the model of critical defect of rats' parietal bone using traditional and three-dimensional morphometry

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Abstract

We modified the techniques of 3D-morphometry using histological sections based on computer-generated ЗЮ reconstruction and mathematical modeling. We compared the results of measurements obtained with the use of above methods and those taken with traditional methods based on the analysis of X-ray pictures. It was shown that the methods of 3D-morphometry we developed provided more precise evaluation of the size of newly formed bone tissue. Basis for technical recommendations to perform the 3D-morphometry at every stage, from surgery to morphological analysis, were proposed.

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3D-modeling / mathematical modeling / regeneration / morphometry / bone tissue

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A. V Vasilyev, A. V Volkov, G. B Bolshakova, D. V Goldstein. Characteristics of neoosteogenesis in the model of critical defect of rats' parietal bone using traditional and three-dimensional morphometry. Genes & Cells, 2014, 9(4): 121-127 DOI:10.23868/gc120414

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