Immunotherapeutic approaches in the treatment of COVID-19

E. V Abakushina

doi:10.23868/202012003

Genes & Cells ›› 2020, Vol. 15 ›› Issue (4) : 19 -26. DOI: 10.23868/202012003

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Immunotherapeutic approaches in the treatment of COVID-19

E. V Abakushina

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Abstract

The novel coronavirus SARS-CoV-2 has caused a life-threatening disease COVID-19 provoked a pandemic over the world. The effectual host immune response including innate and adaptive immunity against SARS-Cov-2 seems crucial to control and resolve the viral infection. However, the severity and outcome of the COVID-19 might be associated with the excessive production of pro-inflammatory cytokines "cytokine storm” leading to an acute respiratory distress syndrome. Regretfully, the exact immunophysiology and treatment, especially for the severe COVID-19, is still uncertain. Novel therapeutic strategies are urgently needed to eliminate the viral reservoir in the host. In this review, we described several potential strategies for immunotherapy to cure SARS-CoV-2 infection. This may provide clue of using immune therapy as combine treatment to prevent the patient develop into severe respiratory syndrome and largely reduced complications.

Keywords

SARS-CoV-2 / Coronavirus disease 201 9 (COVID-1 9) / SARS-CoV-2 / cytokine storm / anti-inflammation treatment / immune therapy

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E. V Abakushina. Immunotherapeutic approaches in the treatment of COVID-19. Genes & Cells, 2020, 15(4): 19-26 DOI:10.23868/202012003

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