THE ANTIMICROBIAL BIODEGRADABLE COMPOSITION BASED ON HIGH-MOLECULAR WEIGHT POLYVINYLPYRROLIDONE FOR THE PROPHYLAXIS OF EXPERIMENTAL OSTHEOMYELITIS

Abstract

The aim of study was to evaluate the efficacy of antimicrobial composition of amikacin with dioxydin and polyvinylpyrrolidone as a biodegradable prolonging agent for the post-surgery infections prophylaxis. The data obtained show the efficacy of the amikacin combination with dioxydin based on high-molecular weight polyvinylpyrrolidone and an opportunity to it's application for the post-surgery infections prophylaxis in traumatology, orthopedics and other surgery areas.

Keywords

osteomyelitis / prophylaxis / experimental study / antimicrobial biodegradable composition

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