Vliyanie tsementnogo i bestsementnogoendoprotezirovaniya krupnykh sustavov na sistemnyyimmunnyy otvet

Marina Vladimirovna Chepeleva; E A Volokitina; N S Shved; D A Kolotygin

doi:10.17816/2311-2905-1924

Traumatology and Orthopedics of Russia ›› :72 -77. DOI: 10.17816/2311-2905-1924

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Vliyanie tsementnogo i bestsementnogoendoprotezirovaniya krupnykh sustavov na sistemnyyimmunnyy otvet

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Abstract

With the purpose of the study of organism systemic immune response to the use of the cement and cementless fixation of endoprostheses in the nearest and remote terms after implantation the analysis of the indices of the immune state of 109 patients with gonarthrosis and coxarthrosis of III stage aged from 40 to 73 was carried out. The authors draw a conclusion that the reaction of immune system to actively functioning implant makes itself by the moderate activation of humoral immunity and the hyperproduction of TNFa against the background of the moderate depression of a cellular component of immune system. The dynamics of the indices of systemic immune response to large joints replacement are conditioned by surgical intervention directly and don't depend on the type of the fixation of implant.

Keywords

arthroplasty / large joints / osteoarthrosis / immunology

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Marina Vladimirovna Chepeleva, E A Volokitina, N S Shved, D A Kolotygin. Vliyanie tsementnogo i bestsementnogoendoprotezirovaniya krupnykh sustavov na sistemnyyimmunnyy otvet. Traumatology and Orthopedics of Russia 72-77 DOI:10.17816/2311-2905-1924

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