Mastoid obliteration using platelet-rich plasma

Abstract

Background: Research and development of new surgical treatments for patients with chronic purulent otitis media are actively carried out in otosurgery as today there is no single generally accepted treatment. This is an urgent task in pediatric practice as hearing loss in children can lead to irreversible consequences for their development.

Aim: To increase the treatment efficacy for children with chronic purulent otitis media with cholesteatoma by improving the mastoid obliteration method.

Methods: From 2019 to 2024, 54 children with chronic purulent otitis media with cholesteatoma were reoperated at the Pediatric Purulent Surgery Department of Krasnoyarsk Interdistrict Children’s Hospital No. 4. In group 1, we used bone chips for mastoid obliteration; in group 2 we used bone chips, platelet-rich plasma, and plasma gel. All children underwent a comprehensive examination at admission and 1 year postoperatively.

Results: In otomicroscopy and non-EPI DWl MSCT/MRI of the temporal bones at 1 year, recurrence of cholesteatoma was detected in 36% of patients in the group where the standard obliteration with bone chips was used. In the group where platelet-rich plasma and plasma gel were used in combination with bone chips, cholesteatoma was detected in 1 patient (4%).

Conclusion: The technique is easy to use and safe. It was effective in patients with chronic purulent otitis media with cholesteatoma.

Keywords

chronic purulent otitis media / cholesteatoma / mastoid obliteration / platelet-rich plasma / plasma gel / bone regeneration

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