Malignant tumors of the sternum in pediatric patients: report of two cases and literature review

Abstract

Destructive changes in the bones are rarely observed in daily practice of pediatric orthopedic surgeons. Clinical and X-ray signs of destructive changes in the bone tissue are characteristic of tumoral, infectious, and inflammatory damages of bones. These signs do not always correspond to a specific disease, and differential diagnostics without histological evaluation is difficult. This is especially true for tumors of the sternum, 85% of which are malignant.

Two rare clinical cases of primary malignant sternal neoplastic lesions in pediatric patients, and a detailed analysis of their clinical, radiologic, and morphologic data are presented. The importance of early histological verification for determining the choice of treatment is demonstrated. A short literature review is also presented.

Keywords

sternum malignant tumor / Hodgkin's lymphoma / children / chondrosarcoma

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RIGHTS & PERMISSIONS

Maletin A.S., Zorin V.I., Gileva V.A., Novitsky T.A., Mushkin A.Y.