Large and giant melanocytic nevi of the maxillofacial area in children: features of the morphological structure and surgical treatment

Abstract

Background. Congenital melanocytic nevus is a benign pigmented neoplasm composed of nevus cells that clinically manifest at birth. When choosing a treatment for nevi, the possibility of recurrence as well as the threat of tumor malignancy should be considered. The aim of this work is to justify the surgical removal of a large and giant nevi of the face as a method of treatment justified by the pathomorphological structure. Materials and Methods. In 40 children of different ages born with large and giant nevi of the face, we used various types of plastic surgery to eliminate any defects formed after the excised nevi. We accounted for the features of the maxillofacial area: local plasty, expander dermotension, and transplantation of free skin grafts. We performed a total of 68 surgical interventions. Sixteen patients underwent the surgery once and 24 patients underwent secondary surgery (from 2 to 4). We also developed a scheme of the staged surgical treatments and conservative methods. Results. All patients had stable positive results that were studied by comparing the outcomes of different surgical treatment options and accounting for various morphological characteristics of the removed nevi.

Keywords

congenital giant melanocytic nevi / congenital large melanocytic nevi / morphological structure / surgical treatment

References

[1] Soyer HH, Argenziano G, Hoffmann-Wellenhof R., Johr RH. (Eds.). Color Atlas of Melanocytic Lesions of the Skin. Сhap. III; Springer, 2007. Р. 106-118. doi: 10.1007/978-3-540-35106-1.

[2] Zaal LH. Giant congenital melanocytic naevi. Amsterdam; 2009. p. 9-37.

[3] Топало В.М. Пигментные невусы лица. - Кишенев: Штиинца, 1985. - С. 15. [Topalo VM. Pigmentnyie nevusyi litsa. Kishenev: Shtiintsa; 1985. p. 15. (In Russ).]

[4] Северин Е.С. Биохимия. - М., 2003. С. 506. [Severin ES. Biokhimiya. Moscow; 2003. Р. 506. (In Russ).]

[5] Касихина Е.И. Гиперпигментация. Современные возможности терапии и профилактики // Лечащий врач. - 2011. - № 6 - С. 73. [Kasikhina EI. Giperpigmentatsiya. Sovremennye vozmozhnosti terapii i profilaktiki. Lechashchiy vrach. 2011;6:73. (In Russ).]

[6] Горделадзе А.С., Новицкая Т.А. Меланоцитарные опухоли. Часть 1. - СПб., 2009. - С. 20-24. [Gordeladze AS, Novitskaya TA. Melanotsitarnye opukholi. Chap. I; Saint-Petersburg, 2009. p. 20-24. (In Russ).]

[7] Ламоткин И.А. Опухоли и опухолеподобные поражения кожи. - М., 2006. - С. 72. [Lamotkin IA. Opukholi i opukholepodobnye porazheniya kozhi. Moscow, 2006. p. 72. (In Russ).]

[8] Пальцев М.А. Неинфекционные заболевания кожи. - М., 2005. - С. 266. [Paltsev MA. Neinfektsionnyie zabolevaniya kozhi. Moscow, 2005. Р. 266. (In Russ).]

[9] Баиндурашвили А.Г., Филиппова О.В., Красногорский И.Н., Цыплакова М.С. Устранение врожденных больших и гигантских пигментных невусов // Клиническая дерматология и венерология. - 2011. - № 4. - С. 29-35. [Baindurashvili AG, Filippova OV, Krasnogorsky IN, Afonichev KA, Tsyplakova MS. Elimination of large and giant congenital pigmented nevi: peculiarities of the treatment strategy. Klin Dermatol Venerol. 2011;4:29-35. (In Russ).]

[10] Цыплакова М.С., Усольцева А.С., Степанова Ю.В. Гигантский врожденный меланоцитарный невус лица. Клинический случай // Травматология, ортопедия и восстановительная хирургия детского возраста. - 2015. - Т. 3. - № 2. - С. 56 [Tsyplakova MS, Usoltseva AS, Stepanova YV. Giant congenital melanocytic nevus of the face. Clinical case. Pediatric Traumatology, Orthopaedics and Reconstructive Surgery. 2015;3(2):56. (In Russ).] doi: 10.17816/PTORS3256-60.

RIGHTS & PERMISSIONS

Usoltseva A.S., Stepanova Y.V., Krasnogorskiy I.N., Tsyplakova M.S.