Lower urinary tract symptoms in men after surgery for benign prostatic hyperplasia
Aleksey V. Krupin , Valentin N. Krupin , Fedor A. Sevryukov
Urology reports (St. - Petersburg) ›› 2024, Vol. 14 ›› Issue (3) : 293 -301.
BACKGROUND: The development of medical technologies has resulted into a significant increase in the number of patients undergoing minimally invasive surgeries for benign prostatic hyperplasia. However, 29.9–41% of patients after surgical treatment are not satisfied with the surgical treatment results.
AIM: To assess the rate and nature of lower urinary tract symptoms in men after surgical treatment of benign prostatic hyperplasia with various surgical techniques.
MATERIALS AND METHODS: A telephone survey was carried out among 6117 men aged 59.57 ± 11.11 years (48–83 years), who underwent surgical treatment for benign prostatic hyperplasia with various surgical techniques and 5960 of these patients were surveyed using the IPSS questionnaire in the period 2012–2022. Moreover, to assess urination, patients kept their voiding diaries for 72 hours, a questionnaire to evaluate the symptoms of overactive bladder; ultrasound of the bladder, prostate and upper urinary tract, uroflowmetry, and, if indicated, a urodynamic study were performed.
RESULTS: The study showed that 2413 (40.5%) patients were “absolutely satisfied” with the surgical treatment results, 829 (13.9%) patients were “partially satisfied” and noted improved urination, although its quality was assessed as unsatisfactory, and 2718 (45.6%) operated men were “absolutely dissatisfied”. Lower urinary tract symptoms persisted in 2655 (47.9%) men which underwent surgery, and in 3.3% of cases (87 patients) their severity increased in the postoperative period.
CONCLUSIONS: The high rate of dissatisfaction with the surgical treatment results of patients with benign prostatic hyperplasia is caused by the persistence of irritative symptoms in the postoperative period and does not depend on the surgery performed. The origin of symptoms in most patients is not associated with benign prostatic hyperplasia, and the surgery indications are overestimated.
prostate gland / lower urinary tract symptoms / LUTS / benign prostatic hyperplasia / BPH / overactive bladder
| [1] |
Kadyrov ZA, Faniev MV, Prokopiev YV, et al. Reproductive health of the Russian population as a key factor of demographic dynamics. The Bulletin of Contemporary Clinical Medicine. 2022;15(5):100–106. EDN: FPJIAU doi: 10.20969/VSKM.2022.15(5).100-106 |
| [2] |
Кадыров З.А., Фаниев М.В., Прокопьев Я.В., и др. Репродуктивное здоровье населения России как ключевой фактор демографической динамики // Вестник современной клинической медицины. 2022. Т. 15, № 5. С. 100–106. EDN: FPJIAU doi: 10.20969/VSKM.2022.15(5).100-106 |
| [3] |
Kadyrov ZA, Faniev MV, Prokopiev YV, et al. Reproductive health of the Russian population as a key factor of demographic dynamics. The Bulletin of Contemporary Clinical Medicine. 2022;15(5):100–106. EDN: FPJIAU doi: 10.20969/VSKM.2022.15(5).100-106 |
| [4] |
Apolihin OI, Sevryukov FA, Sorokin DA, et al. Dynamics and prognosis of the benign prostatic hyperplasia morbidity in Nizhegorodsky region. Experimental and clinical urology. 2013;(3):4–7. EDN: REDDGB |
| [5] |
Аполихин О.И., Севрюков Ф.А., Сорокин Д.А., и др. Динамика и прогнозы заболеваемости доброкачественной гиперплазией предстательной железы в Нижегородской области // Экспериментальная и клиническая урология. 2013. № 3. С. 4–7. EDN: REDDGB |
| [6] |
Apolihin OI, Sevryukov FA, Sorokin DA, et al. Dynamics and prognosis of the benign prostatic hyperplasia morbidity in Nizhegorodsky region. Experimental and clinical urology. 2013;(3):4–7. EDN: REDDGB |
| [7] |
Sevryukov FA, Sorokin DA, Karpuhin IV, et al. Transurethral enucleation of prostate (TUEB) — new option in bipolar endoscopic surgery of BPH. Experimental and clinical urology. 2012;(2):34–36. EDN: PDARMH |
| [8] |
Севрюков Ф.А., Сорокин Д.А., Карпухин И.В., и др. Трансуретральная энуклеация предстательной железы (TUEB) — новый метод биполярной эндоскопической хирургии ДГПЖ // Экспериментальная и клиническая урология. 2012. № 2. С. 34–36. EDN: PDARMH |
| [9] |
Sevryukov FA, Sorokin DA, Karpuhin IV, et al. Transurethral enucleation of prostate (TUEB) — new option in bipolar endoscopic surgery of BPH. Experimental and clinical urology. 2012;(2):34–36. EDN: PDARMH |
| [10] |
Mustafaev AT, Kyzlasov PS, Dianov MP, et al. Surgical treatment of benign prostatic hyperplasia: the past and the present. Urology reports (St. Petersburg). 2019;9(1):47–56. EDN ICSZAV doi: 10.17816/uroved9147-56 |
| [11] |
Мустафаев А.Т., Кызласов П.С., Дианов М.П., и др. Хирургическое лечение доброкачественной гиперплазии предстательной железы: прошлое и настоящее // Урологические ведомости. 2019. Т. 9, № 1. C. 47–56. EDN: ICSZAV doi: 10.17816/uroved9147-56 |
| [12] |
Mustafaev AT, Kyzlasov PS, Dianov MP, et al. Surgical treatment of benign prostatic hyperplasia: the past and the present. Urology reports (St. Petersburg). 2019;9(1):47–56. EDN ICSZAV doi: 10.17816/uroved9147-56 |
| [13] |
Pushkar DYu, Rasner PI. Lower urinary tract symptoms and benign prostatic hyperplasia. Urologiia. 2006;(3S):4–18. EDN: YZMCGP doi: 10.18565/urol.2017.3-supplement.4-18 |
| [14] |
Пушкарь Д.Ю., Раснер П.И. Симптомы нижних мочевыводящих путей и доброкачественная гиперплазия предстательной железы // Урология. 2006. № 3S. С. 4–18. EDN: YZMCGP doi: 10.18565/urol.2017.3-supplement.4-18 |
| [15] |
Pushkar DYu, Rasner PI. Lower urinary tract symptoms and benign prostatic hyperplasia. Urologiia. 2006;(3S):4–18. EDN: YZMCGP doi: 10.18565/urol.2017.3-supplement.4-18 |
| [16] |
www.nice.org.uk [Internet]. National Institute for Health and Clinical Excellence. The management of lower urinary tract symptoms in men & Appendices A-H. Available from: http://www.nice.org.uk/nicemedia/live/12984/48554/48554.pdf |
| [17] |
www.nice.org.uk [Электронный ресурс]. National Institute for Health and Clinical Excellence. The management of lower urinary tract symptoms in men & Appendices A-H. Режим доступа: http://www.nice.org.uk/nicemedia/live/12984/48554/48554.pdf |
| [18] |
www.nice.org.uk [Internet]. National Institute for Health and Clinical Excellence. The management of lower urinary tract symptoms in men & Appendices A-H. Available from: http://www.nice.org.uk/nicemedia/live/12984/48554/48554.pdf |
| [19] |
Lepor H, Rigaud G. The efficacy of transurethral resection of the prostate in men with moderate symptoms of prostatism. J Urol. 1990;143(3):533–537. doi: 10.1016/s0022-5347(17)40012-7 |
| [20] |
Lepor H., Rigaud G. The efficacy of transurethral resection of the prostate in men with moderate symptoms of prostatism // J Urol. 1990. Vol. 143, N 3. P. 533–537. doi: 10.1016/s0022-5347(17)40012-7 |
| [21] |
Lepor H, Rigaud G. The efficacy of transurethral resection of the prostate in men with moderate symptoms of prostatism. J Urol. 1990;143(3):533–537. doi: 10.1016/s0022-5347(17)40012-7 |
| [22] |
Sevryukov FA. Choice of the method of urodynamic examination of patients in determining the indications for surgical treatment of benign prostatic hyperplasia [dissertation abstract]. Moscow; 1999. 25 p. (In Russ.) |
| [23] |
Севрюков Ф.А. Выбор метода уродинамического обследования больных при определении показаний к оперативному лечению доброкачественной гиперплазии предстательной железы: автореф. дис. … канд. мед. наук. Москва, 1999. 25 с. |
| [24] |
Sevryukov FA. Choice of the method of urodynamic examination of patients in determining the indications for surgical treatment of benign prostatic hyperplasia [dissertation abstract]. Moscow; 1999. 25 p. (In Russ.) |
| [25] |
Pushkar DY. “Successful” transurethral resection of the prostate in the Russian Federation. In: XVII Congress of the Russian Society of Urologists: “Effective Pharmacotherapy. Urology and Nephrology”. N 2. 2017. (In Russ.) https://umedp.ru/articles/print/11949 |
| [26] |
Пушкарь Д.Ю. «Успешная» трансуретральная резекция простаты в РФ. В кн.: XVII Конгресс Российского общества урологов: «Эффективная фармакотерапия. Урология и Нефрология». № 2. 2017. https://umedp.ru/articles/print/11949 |
| [27] |
Pushkar DY. “Successful” transurethral resection of the prostate in the Russian Federation. In: XVII Congress of the Russian Society of Urologists: “Effective Pharmacotherapy. Urology and Nephrology”. N 2. 2017. (In Russ.) https://umedp.ru/articles/print/11949 |
| [28] |
Simanov RN, Amdiy RE, Kuzmin IV. Features of detrusor function disorders in patients with dysuria in the long period after transurethral resection of the prostate. Urology reports (St. Petersburg). 2024;14(1):35–44. EDN: HRJIIS doi: 10.17816/uroved619917 |
| [29] |
Симанов Р.Н., Амдий Р.Э., Кузьмин И.В. Особенности нарушений функции детрузора у пациентов с дизурией в отдаленном периоде после трансуретральной резекции предстательной железы // Урологические ведомости. 2024. Т. 14, № 1. C. 35–44. EDN: HRJIIS doi: 10.17816/uroved619917 |
| [30] |
Simanov RN, Amdiy RE, Kuzmin IV. Features of detrusor function disorders in patients with dysuria in the long period after transurethral resection of the prostate. Urology reports (St. Petersburg). 2024;14(1):35–44. EDN: HRJIIS doi: 10.17816/uroved619917 |
| [31] |
Cornu J-N, Ahyai S, Bachmann A, et al. A systematic review and meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic obstruction: An update. Eur Urol. 2015;67(6):1066–1096. doi: 10.1016/j.eururo.2014.06.017 |
| [32] |
Cornu J.-N., Ahyai S., Bachmann A., et al. A systematic review and meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic obstruction: An update // Eur Urol. 2015. Vol. 67, N 6. P. 1066–1096. doi: 10.1016/j.eururo.2014.06.017 |
| [33] |
Cornu J-N, Ahyai S, Bachmann A, et al. A systematic review and meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic obstruction: An update. Eur Urol. 2015;67(6):1066–1096. doi: 10.1016/j.eururo.2014.06.017 |
| [34] |
Kuzmin IV. Epidemiological aspects of overactive bladder and urge urinary incontinence. Urology reports (St. Petersburg). 2015;5(3):30–34. EDN: VHUCCH doi:10.17816/uroved5330-3 |
| [35] |
Кузьмин И.В. Эпидемиологические аспекты гиперактивного мочевого пузыря и ургентного недержания мочи // Урологические ведомости. 2015. Т. 5, № 3. C. 30–34. EDN: VHUCCH doi: 10.17816/uroved5330-3 |
| [36] |
Kuzmin IV. Epidemiological aspects of overactive bladder and urge urinary incontinence. Urology reports (St. Petersburg). 2015;5(3):30–34. EDN: VHUCCH doi:10.17816/uroved5330-3 |
| [37] |
Simanov RN, Amdiy RE, Al-Shukri SK, et al. Effectiveness of treatment of detrusor overactivity after transurethral resection of benign prostate hyperplasia. Urology reports (St. Petersburg). 2023;13(1):5–13. EDN: GUAKSQ doi: 10.17816/uroved192493 |
| [38] |
Симанов Р.Н., Амдий Р.Э., Аль-Шукри С.Х., и др. Эффективность лечения гиперактивности детрузора после трансуретральной резекции доброкачественной гиперплазии предстательной железы // Урологические ведомости. 2023. Т. 13, № 1. C. 5–13. EDN: GUAKSQ doi: 10.17816/uroved192493 |
| [39] |
Simanov RN, Amdiy RE, Al-Shukri SK, et al. Effectiveness of treatment of detrusor overactivity after transurethral resection of benign prostate hyperplasia. Urology reports (St. Petersburg). 2023;13(1):5–13. EDN: GUAKSQ doi: 10.17816/uroved192493 |
| [40] |
Ivashchenko VA. Diagnosis and treatment of urinary disorders after transurethral resection of the prostate in patients with benign prostatic hyperplasia [dissertation]. Chelyabinsk; 2017. 179 p. (In Russ.) |
| [41] |
Иващенко В.А. Диагностика и лечение расстройств мочеиспускания после трансуретральной резекции простаты у больных доброкачественной гиперплазией предстательной железы: дис. … канд. мед. наук. Челябинск, 2017. 179 с. |
| [42] |
Ivashchenko VA. Diagnosis and treatment of urinary disorders after transurethral resection of the prostate in patients with benign prostatic hyperplasia [dissertation]. Chelyabinsk; 2017. 179 p. (In Russ.) |
| [43] |
Amdii RE. Diagnostic and prognostic value of lower urinary tract urodynamic studies in patients with infravesical obstruction and impaired detrusor contractility [dissertation]. Saint Petersburg; 2007. 336 p. (In Russ.) |
| [44] |
Амдий Р.Э. Диагностическое и прогностическое значение уродинамических исследований нижних мочевых путей у больных инфравезикальной обструкцией и нарушением сократимости детрузора: дис. … д-ра мед. наук. Санкт-Петербург, 2007. 336 с. |
| [45] |
Amdii RE. Diagnostic and prognostic value of lower urinary tract urodynamic studies in patients with infravesical obstruction and impaired detrusor contractility [dissertation]. Saint Petersburg; 2007. 336 p. (In Russ.) |
| [46] |
Nitti VW, Kim Y, Combs AJ. Voiding dysfunction following transurethral resection of the prostate: symptoms and urodynamic findings. J Urol. 1997;157(2):600–603. doi: 10.1016/S0022-5347(01)65214-5 |
| [47] |
Nitti V.W., Kim Y., Combs A.J. Voiding dysfunction following transurethral resection of the prostate: symptoms and urodynamic findings // J Urol. 1997. Vol. 157, N 2. P. 600–603. doi: 10.1016/S0022-5347(01)65214-5 |
| [48] |
Nitti VW, Kim Y, Combs AJ. Voiding dysfunction following transurethral resection of the prostate: symptoms and urodynamic findings. J Urol. 1997;157(2):600–603. doi: 10.1016/S0022-5347(01)65214-5 |
| [49] |
Amdiy RE, Giorgobiani TG. Evaluation of the lower urinary tract dysfunction at patients with unsatisfactory results operative treatment benign prostatic hyperplasia. Urology reports (St. Petersburg). 2012;2(2):32–37. EDN: PZHTGH doi: 10.17816/uroved2232-37 |
| [50] |
Амдий Р.Э., Гиоргобиани Т.Г. Диагностика нарушений функции нижних мочевых путей у больных с неудовлетворительными результатами оперативного лечения доброкачественной гиперплазии предстательной железы // Урологические ведомости. 2012. Т. 2, № 2. C. 32–37. EDN: PZHTGH doi: 10.17816/uroved2232-37 |
| [51] |
Amdiy RE, Giorgobiani TG. Evaluation of the lower urinary tract dysfunction at patients with unsatisfactory results operative treatment benign prostatic hyperplasia. Urology reports (St. Petersburg). 2012;2(2):32–37. EDN: PZHTGH doi: 10.17816/uroved2232-37 |
| [52] |
Martov AG, Merinov DS, Kornienko SI, et al. Postoperative urologic complications of transurethral electrosurgical interventions on the prostate gland for adenoma. Urologiia. 2006;(2):25–32. (In Russ.) |
| [53] |
Мартов А.Г., Меринов Д.С., Корниенко С.И., и др. Послеоперационные урологические осложнения трансуретральных электрохирургических вмешательств на предстательной железе по поводу аденомы // Урология. 2006. № 2. С. 25–32. |
| [54] |
Martov AG, Merinov DS, Kornienko SI, et al. Postoperative urologic complications of transurethral electrosurgical interventions on the prostate gland for adenoma. Urologiia. 2006;(2):25–32. (In Russ.) |
| [55] |
Nozdrachev NA, Neimark AI, Neimark BA. Administration of Vitaprost plus for prevention of infectious-inflammatory complications of transurethral prostatic resection in patients with prostatic adenoma. Urologiia. 2011;(4):55–59. EDN: OEZORF |
| [56] |
Неймарк А.И., Неймарк Б.А., Ноздрачев Н.А. Применение Витапрост Плюс в профилактике инфекционно-воспалительных осложнений при проведении ТУР аденомы предстательной железы // Урология. 2011. № 4. С. 55–59. EDN: OEZORF |
| [57] |
Nozdrachev NA, Neimark AI, Neimark BA. Administration of Vitaprost plus for prevention of infectious-inflammatory complications of transurethral prostatic resection in patients with prostatic adenoma. Urologiia. 2011;(4):55–59. EDN: OEZORF |
| [58] |
Pereverzev AS, Sergienko NF, Ilyukhin SA. Diseases of the prostate gland. Kharkov: S.A.M. Publ.; 2005. 260 p. (In Russ.) |
| [59] |
Переверзев А.С., Сергиенко Н.Ф., Илюхин Ю.А. Заболевания предстательной железы. Харьков: С.А.М., 2005. 260 с. |
| [60] |
Pereverzev AS, Sergienko NF, Ilyukhin SA. Diseases of the prostate gland. Kharkov: S.A.M. Publ.; 2005. 260 p. (In Russ.) |
| [61] |
Tkachuk IN. Complications of transurethral resection of prostate in patients with benign prostatic hyperplasia and ways of their prevention [dissertation]. Saint Petersburg; 2011. 166 p. (In Russ.) |
| [62] |
Ткачук И.Н. Осложнения трансуретральной резекции простаты у больных доброкачественной гиперплазией предстательной железы и пути их профилактики: дис. … канд. мед. наук. Санкт-Петербург, 2011. 166 с. |
| [63] |
Tkachuk IN. Complications of transurethral resection of prostate in patients with benign prostatic hyperplasia and ways of their prevention [dissertation]. Saint Petersburg; 2011. 166 p. (In Russ.) |
| [64] |
Nickel JC, Downey J, Pontari MA, et al. A randomized placebo-controlled multicentre study to evaluate the safety and efficacy of finasteride for male chronic pelvic pain syndrome (category IIIA chronic nonbacterial prostatitis). BJU Int. 2004;93(7):991–995. doi: 10.1111/j.1464-410X.2003.04766.x |
| [65] |
Nickel J.C., Downey J., Pontari M.A., et al. A randomized placebo-controlled multicentre study to evaluate the safety and efficacy of finasteride for male chronic pelvic pain syndrome (category IIIA chronic nonbacterial prostatitis) // BJU Int. 2004. Vol. 93, N 7. P. 991–995. doi: 10.1111/j.1464-410X.2003.04766.x |
| [66] |
Nickel JC, Downey J, Pontari MA, et al. A randomized placebo-controlled multicentre study to evaluate the safety and efficacy of finasteride for male chronic pelvic pain syndrome (category IIIA chronic nonbacterial prostatitis). BJU Int. 2004;93(7):991–995. doi: 10.1111/j.1464-410X.2003.04766.x |
| [67] |
Mazo EB, Krivoborodov GG, Shkolnikov ME, Gorchkhanov MA. Diagnosis and treatment of chronic pelvic pain syndrome in men. Lechaschi vrach. 2004;(9). Available from: https://www.lvrach.ru/2004/09/4531672?ysclid=m1b244p5y859221173 (In Russ.) |
| [68] |
Мазо Е.Б., Кривобородов Г.Г., Школьников М.Е., Горчханов М.А. Диагностика и лечение синдрома хронической тазовой боли у мужчин // Лечащий Врач. 2004. № 9. Режим доступа: https://www.lvrach.ru/2004/09/4531672?ysclid=m1b244p5y859221173 |
| [69] |
Mazo EB, Krivoborodov GG, Shkolnikov ME, Gorchkhanov MA. Diagnosis and treatment of chronic pelvic pain syndrome in men. Lechaschi vrach. 2004;(9). Available from: https://www.lvrach.ru/2004/09/4531672?ysclid=m1b244p5y859221173 (In Russ.) |
| [70] |
Startsev VYu, Dudarev VA, Sevryukov FA, Zabrodina NB. Economic aspects of treatment for lower urinary tract symptoms associated with benign prostatic hyperplasia. Urologiia. 2019;(6):115–119. EDN: DBIZTQ doi: 10.18565/urology.2019.6.115-119 |
| [71] |
Старцев В.Ю., Дударев В.А., Севрюков Ф.А., Забродина Н.Б. Экономические аспекты лечения больных с нарушениями мочеиспускания, обусловленными доброкачественной гиперплазией предстательной железы // Урология. 2019. № 6. С. 115–119. EDN: DBIZTQ doi: 10.18565/urology.2019.6.115-119 |
| [72] |
Startsev VYu, Dudarev VA, Sevryukov FA, Zabrodina NB. Economic aspects of treatment for lower urinary tract symptoms associated with benign prostatic hyperplasia. Urologiia. 2019;(6):115–119. EDN: DBIZTQ doi: 10.18565/urology.2019.6.115-119 |
| [73] |
Kuzmin IV, Slesarevskaya MN, Romikh VV. Overactive bladder, inflammation and urinary tract infection: pathogenetic parallels. Urology reports (St. Petersburg). 2024;14(1):65–79. EDN: GAHDJA doi: 10.17816/uroved627461 |
| [74] |
Кузьмин И.В., Слесаревская М.Н., Ромих В.В. Гиперактивный мочевой пузырь, воспаление и инфекция мочевыводящих путей: патогенетические параллели // Урологические ведомости. 2024. Т. 14, № 1. C. 65–79. EDN: GAHDJA doi: 10.17816/uroved627461 |
| [75] |
Kuzmin IV, Slesarevskaya MN, Romikh VV. Overactive bladder, inflammation and urinary tract infection: pathogenetic parallels. Urology reports (St. Petersburg). 2024;14(1):65–79. EDN: GAHDJA doi: 10.17816/uroved627461 |
| [76] |
Avdoshin VP, Aslamazov EA, Goryunov VG, et al. Manual of urology. In 3 vol. Vol. 2. Lopatkin NA, editor. Moscow: Medicine; 1998. 764 p. (In Russ.) |
| [77] |
Авдошин В.П., Асламазов Э.А., Горюнов В.Г., и др. Руководство по урологии. В 3 т. Т. 2 / под ред. Н.А. Лопаткина. Москва: Медицина, 1998. 764 c. |
| [78] |
Avdoshin VP, Aslamazov EA, Goryunov VG, et al. Manual of urology. In 3 vol. Vol. 2. Lopatkin NA, editor. Moscow: Medicine; 1998. 764 p. (In Russ.) |
| [79] |
He W, Ding T, Niu Z, et al. Reoperation after surgical treatment for benign prostatic hyperplasia: a systematic review. Front Endocrinol (Lausanne). 2023;14:1287212. doi: 10.3389/fendo.2023.1287212 |
| [80] |
He W., Ding T., Niu Z., et al. Reoperation after surgical treatment for benign prostatic hyperplasia: a systematic review // Front Endocrinol (Lausanne). 2023. Vol. 14. ID 1287212. doi: 10.3389/fendo.2023.1287212 |
| [81] |
He W, Ding T, Niu Z, et al. Reoperation after surgical treatment for benign prostatic hyperplasia: a systematic review. Front Endocrinol (Lausanne). 2023;14:1287212. doi: 10.3389/fendo.2023.1287212 |
| [82] |
Sitdykov RM, Shaidullin EN, Zubkov AY. Choosing the surgical treatment method for benign prostatic hyperplasia. Kazan medical journal. 2013;94(3):409–412. EDN: RRRRQP doi: 10.17816/KMJ2196 |
| [83] |
Шайдуллин Р.М., Ситдыков Э.Н., Зубков А.Ю. Выбор метода оперативного лечения аденомы предстательной железы // Казанский медицинский журнал. 2013. Т. 94, № 3. C. 409–412. EDN: RRRRQP doi: 10.17816/KMJ2196 |
| [84] |
Sitdykov RM, Shaidullin EN, Zubkov AY. Choosing the surgical treatment method for benign prostatic hyperplasia. Kazan medical journal. 2013;94(3):409–412. EDN: RRRRQP doi: 10.17816/KMJ2196 |
| [85] |
Jensen KM, Andersen JT. Urodynamic implications of benign prostatic hyperplasia. Urologe A. 1990;29(1): 1–4. |
| [86] |
Jensen K.M., Andersen J.T. Urodynamic implications of benign prostatic hyperplasia // Urologe A. 1990. Vol. 29, N 1. P. 1–4. |
| [87] |
Jensen KM, Andersen JT. Urodynamic implications of benign prostatic hyperplasia. Urologe A. 1990;29(1): 1–4. |
| [88] |
Nielsen KK, Andersen CB, Petersen LK, et al. Morphological, stereological, and biochemical analysis of the mini-pig urinary bladder after chronic outflow obstruction and after recovery from obstruction. Neurourol Urodyn. 1995;14(3):269–284. doi: 10.1002/nau.1930140308 |
| [89] |
Nielsen K.K., Andersen C.B., Petersen L.K., et al. Morphological, stereological, and biochemical analysis of the mini-pig urinary bladder after chronic outflow obstruction and after recovery from obstruction // Neurourol Urodyn. 1995. Vol. 14, N 3. P. 269–284. doi: 10.1002/nau.1930140308 |
| [90] |
Nielsen KK, Andersen CB, Petersen LK, et al. Morphological, stereological, and biochemical analysis of the mini-pig urinary bladder after chronic outflow obstruction and after recovery from obstruction. Neurourol Urodyn. 1995;14(3):269–284. doi: 10.1002/nau.1930140308 |
| [91] |
Aganovic D, Hasanbegovic M, Prcic A, et al. Which is a better indicator of bladder outlet obstruction in patients with benign prostatic enlargement — intravesical protrusion of prostate or bladder wall thickness? Med Arch. 2012;66(5):324–328. doi: 10.5455/medarh.2012.66.324-328 |
| [92] |
Aganovic D., Hasanbegovic M., Prcic A., et al. Which is a better indicator of bladder outlet obstruction in patients with benign prostatic enlargement — intravesical protrusion of prostate or bladder wall thickness? // Med Arch. 2012. Vol. 66, N 5. P. 324–328. doi: 10.5455/medarh.2012.66.324-328 |
| [93] |
Aganovic D, Hasanbegovic M, Prcic A, et al. Which is a better indicator of bladder outlet obstruction in patients with benign prostatic enlargement — intravesical protrusion of prostate or bladder wall thickness? Med Arch. 2012;66(5):324–328. doi: 10.5455/medarh.2012.66.324-328 |
| [94] |
Kuo H-C. Analysis of the pathophysiology of lower urinary tract symptoms in patients after prostatectomy. Urol Int. 2002;68(2): 99–104. doi: 10.1159/000048427 |
| [95] |
Kuo H.-C. Analysis of the pathophysiology of lower urinary tract symptoms in patients after prostatectomy // Urol Int. 2002. Vol. 68, N 2. P. 99–104. doi: 10.1159/000048427 |
| [96] |
Kuo H-C. Analysis of the pathophysiology of lower urinary tract symptoms in patients after prostatectomy. Urol Int. 2002;68(2): 99–104. doi: 10.1159/000048427 |
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