The effect of the phytocomplex Renotineх® on postoperative period after external shock wave lithotripsy in patients with urolithiasis
Aleksandr I. Neymark , Boris A. Neymark , Nikolay A. Nozdrachev , Michail Y. Gatkin , Yulia S. Fursa
Urology reports (St. - Petersburg) ›› 2021, Vol. 11 ›› Issue (1) : 49 -54.
The effect of the phytocomplex Renotineх® on postoperative period after external shock wave lithotripsy in patients with urolithiasis
INTRODUCTION: Phytopreparations are one of the leading medicines used as preoperative preparation and postoperative management in patients with urolithiasis.
THE AIM of the study was to evaluate the nephroprotective effect of Renotinex® in patients with urolithiasis after extracorporeal shock wave lithotripsy (ESWL).
MATERIALS AND METHODS: The study included 86 patients (43 in the main and the comparison group) with urolithiasis with localization of the stone in the renal pelvis without disturbing the outflow of urine. All patients underwent extracorporeal shock wave lithotripsy (ESWL). After ESWL patients in both groups received spasmodic, anti-inflammatory, antibacterial therapy. Patients of the main group additionally received Renotinex® 2 capsules 3 times a day for 14 days before and 14 days after surgery.
RESULTS: During the observation a more effective discharge of calculus fragments was noted in patients of the main group while taking the phytocomplex Renotinex®, as well as less pronounced damage and faster recovery of the renal parenchyma after ESWL according to the level of enzimuria.
CONCLUSION: The results of the study indicate the feasibility of prescribing the phytocomplex Renotinex® for nephroprotective and lithokinetic therapy in patients after ESWL.
urolithiasis / herbal medicine / Renotinex® / enzymuria / nephroprotective therapy
| [1] |
Apolikhin OI, Sivkov AV, Moskaleva NG, et al. Analysis of the uro-nephrological morbidity and mortality in the Russian Federation during the 10-year period (2002–2012) according to the official statistics. Experimental and Clinical Urology. 2014;(2):4–13. (In Russ.) |
| [2] |
Аполихин О.И., Сивков А.В., Москалева Н.Г., и др. Анализ уронефрологической заболеваемости и смертности в Российской Федерации за десятилетний период (2002–2012 гг.) по данным официальной статистики // Экспериментальная и клиническая урология. 2014. № 2. С. 4–13. |
| [3] |
Alyaev YuG, Glybochko PV, Pushkar DYu. Urology. Russian clinical recommendations. Moscow: Medforum; 2017;78–126. (In Russ.) |
| [4] |
Аляев Ю.Г., Глыбочко П.В., Пушкарь Д.Ю. Урология. Российские клинические рекомендации. М.: Медфорум, 2017. C. 78–126. |
| [5] |
Rudenko VI, Semenyakin IV, Malkhasyan VA, Gadzhiev NK. Urolythiasis. Urologiya. 2017;(2 S2):30–63. (In Russ.) |
| [6] |
Руденко В.И., Семенякин И.В., Малхасян В.А., Гаджиев Н.К. Мочекаменная болезнь // Урология. 2017. № 2-S2. С. 30–63. |
| [7] |
Ensebaev EZ, Bajgaskinov ZK. Results of extracorporeal shock wave lithotripsy in patients with high density kidney calculi. Urology reports (St. Petersburg). 2020;10(3):235–241. (In Russ.) DOI: 10.17816/uroved33783 |
| [8] |
Енсебаев Е.Ж., Байгаскинов Ж.К. Результаты дистанционной литотрипсии у пациентов с конкрементами почек высокой плотности // Урологические ведомости. 2020. Т. 10, № 3. C. 235–241. DOI: 10.17816/uroved33783 |
| [9] |
Khasigov AV, Khazhokov MA, Ilyash AV, et al. Effectiveness and safety of extracorporeal shockwave lithotripsy for uncomplicated pelvic concrements. Urology Herald. 2017;5(3):39–48. (In Russ.) DOI: 10.21886/2308-6424-2017-5-3-39-48 |
| [10] |
Хасигов А.В., Хажоков М.А., Ильяш А.В., и др. Эффективность и безопасность дистанционной ударно-волновой литотрипсии простых лоханочных камней // Вестник урологии. 2017. Т. 5. № 3. С. 39–48. DOI: 10.21886/2308-6424-2017-5-3-39-48 |
| [11] |
Sitdykova ME, Kuzmina FM. Efficacy of a plant complex prolit after extracorporeal lithotripsy in patients with urolithiasis. Urologiia. 2006;(3):57–60. (In Russ.) |
| [12] |
Ситдыкова М.Э., Кузьмина Ф.М. Эффективность применения «Пролита» у больных мочекаменной болезнью после дистанционной литотрипсии // Урология. 2006. № 3. C. 57–60. |
| [13] |
Popkov VM, Osnovin OV, Fomkina OA. Results of using of terpens-based medication renotinex in patients with urolithiasis after extracorporeal shockwave lithotripsy. Urology reports (St. Petersburg). 2020;10(1):39–42. (In Russ.) DOI: 10.17816/uroved10139–42 |
| [14] |
Попков В.М., Основин О.В., Фомкина О.А. Результаты применения препарата на основе терпенов Ренотинекс у пациентов с уролитиазом после дистанционной ударно-волновой литотрипсии // Урологические ведомости. 2020. Т. 10. № 1. C. 39–42. DOI: 10.17816/uroved10139-42 |
| [15] |
Sharaev PN, Gabdrahmanova NK, Strelkova TN, Sahabutdinova EP. A method of determining the activity of N-acetyl-β-D-hexosaminidase in urea. Russian Clinical Laboratory Diagnostics. 2004;(5):40–42 (In Russ.) |
| [16] |
Шараев П.Н., Габдрахманова Н.К., Стрелкова Т.Н., Сахабутдинова Е.П. Способ определения активности N-ацетил-β-D-гексозаминидазы в моче // Клиническая лабораторная диагностика. 2004. № 5. С. 40–42. |
| [17] |
Glanc S. Primer of Biostatistics. M.: Praktika; 1998. P. 459. (In Russ.) |
| [18] |
Гланц С. Медико-биологическая статистика / пер. с англ. М.: Практика, 1998; 459 с. |
| [19] |
Kehrer G, Blech M, Kallerhoff M, Bretschneider HJ. Urinary LDH-release for evaluation of postischemic renal function. Klin Wochenschr. 1989;67(9):477–485. DOI: 10.1007/BF01721673. |
| [20] |
Kehrer G., Blech M., Kallerhoff M., Bretschneider H.J. Urinary LDH-release for evaluation of postischemic renal function // Klin Wochenschr. 1989. Vol. 67, No. 9. P. 477–485. DOI: 10.1007/BF01721673. |
Eco-Vector
/
| 〈 |
|
〉 |