THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS

T V Stavenchuk; E D Kosmachova; I A Shelestova; A A Slavinsky; E A Terman; A A Verevkin; L A Medvedeva; K O Barbuhatty; Z G Tatarintseva; V A Porchanov

doi:10.17816/clinpract8328-33

Journal of Clinical Practice ›› 2017, Vol. 8 ›› Issue (3) : 28 -33. DOI: 10.17816/clinpract8328-33

Articles

research-article

THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS

Author information +

History +

PDF

Abstract

The following article describes tactics of recipient management when a rejection episode of a heart transplant is being suspected. We have discovered some new figures to assess biopsy samples through computerised morphometric study, which can both improve and clarify biopsy results. CD3+ (T-cells) and CD 68+ (macrophages) figures make it possible to determine the extent of transplant rejection in accordance with the International Society for Heart and Lung Transplantation diagnostic criteria (sensitivity 91%, specificity 91%).

Keywords

computerised morphometric study / endomyocardial biopsy / heart transplant rejection

Cite this article

Download citation ▾

T V Stavenchuk,E D Kosmachova,I A Shelestova,A A Slavinsky,E A Terman,A A Verevkin,L A Medvedeva,K O Barbuhatty,Z G Tatarintseva,V A Porchanov. THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS. Journal of Clinical Practice, 2017, 8(3): 28-33 DOI:10.17816/clinpract8328-33

登录浏览全文

4963

注册一个新账户忘记密码

References

Publishing order | Descend order by publishing year | Descend order by cited within

RIGHTS & PERMISSIONS

Stavenchuk T.V., Kosmachova E.D., Shelestova I.A., Slavinsky A.A., Terman E.A., Verevkin A.A., Medvedeva L.A., Barbuhatty K.O., Tatarintseva Z.G., Porchanov V.A.