USE OF AN AQUEOUS SOLUTION «PHOTODITAZIN», COMPLEXED WITH A VARIETY OF POLYMERS FORTHE TREATMENT OF PURULENT WOUNDS OF SOFT TISSUE EXPERIMENT

A B Solovyeva; A L Spokoyniy; T G Rudenko; A B Shekhter; N N Glagolev; N A Aksenova; A V Baranov

doi:10.17816/clinpract7245-49

Journal of Clinical Practice ›› 2016, Vol. 7 ›› Issue (2) : 45 -49. DOI: 10.17816/clinpract7245-49

Articles

research-article

USE OF AN AQUEOUS SOLUTION «PHOTODITAZIN», COMPLEXED WITH A VARIETY OF POLYMERS FORTHE TREATMENT OF PURULENT WOUNDS OF SOFT TISSUE EXPERIMENT

Author information +

History +

PDF

Abstract

The article presents the results of a study of water-soluble polymers effects on the “Photoditazin” activity and the course of wound process under photodynamic therapy of purulent wounds in rats. The data of macroscopic and histological study of wounds status before and after photodynamic therapy, and assessed the quality and degree of intensity of reparative processes under influence of photodynamic therapy with the drug “Photoditazin” and its complexes with water-soluble polymers of natural poly- saccharide chitosan and a triple block copolymer of ethylene- and propylene oxide (pluronic F127).It was given the rationale for Pluronic F127 joining to the drug “Photoditazine” for reducing the cytotoxic effects of the drug.

Keywords

photodynamic therapy / “Photoditazine” / treatment of wounds

Cite this article

Download citation ▾

A B Solovyeva, A L Spokoyniy, T G Rudenko, A B Shekhter, N N Glagolev, N A Aksenova, A V Baranov. USE OF AN AQUEOUS SOLUTION «PHOTODITAZIN», COMPLEXED WITH A VARIETY OF POLYMERS FORTHE TREATMENT OF PURULENT WOUNDS OF SOFT TISSUE EXPERIMENT. Journal of Clinical Practice, 2016, 7(2): 45-49 DOI:10.17816/clinpract7245-49

登录浏览全文

4963

注册一个新账户忘记密码

References

Publishing order | Descend order by publishing year | Descend order by cited within

[1]	Толстых П.И. Лечение ишемических язв, развившихся на фоне атеросклероза сосудов нижних конечностей // Лазерная медицина. 2013. Т.17 № 2. С. 40-44.

[2]	Толстых П.И., Соловьева А.Б., Дербенев В.А., Спокойный А.Л. и др. Сравнительная эффективность лекарственных форм сенсибилизаторов, применяемых при фотодинамической терапии гнойных ран // Лазерная медицина. 2014. Т.18. № 2. С.8-12.

[3]	Толстых П.И., Соловьева А.Б., Спокойный А.Л. Оптимизация фотохимической терапии гнойных ран мягких тканей //Лазерная медицина. 2014 Т.18. №4. С.26.

[4]	Shekhter A.B. Beneficial effect of gaseous nitric oxide on the healing of skin wounds Nitric Oxide // Photochemistryistry and Photobiologyogy. 2013. Vol. 12. №4. P.210-219.

[5]	Solovieva A.V., Aksenova N.A., Sorokaty A.A. , A.L. Spokoyniy. Photodynamic therapy of intractable purulent wounds with photoditazine-polymer complex immobilized on hydroxyapatite nanoparticles // Photodiagnosis and Photodynamic Therapy. 2012. Vol.9. Supplement 1. P.14.