EXPRESSION OF OCT-4, P53, P16 AND KI-67, WITH HPV ASSOCIATED PRECANCER AND CANCER OF THE CERVIX

E A Kogan; Li Ts Ts; N M Faizullina; A V Kazachenko

doi:10.17816/clinpract7134-38

Journal of Clinical Practice ›› 2016, Vol. 7 ›› Issue (1) : 34 -38. DOI: 10.17816/clinpract7134-38

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EXPRESSION OF OCT-4, P53, P16 AND KI-67, WITH HPV ASSOCIATED PRECANCER AND CANCER OF THE CERVIX

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Abstract

The pathology of cervical HPV infection is detected by three types of epithelial-mesenchymal spheroidal structures: reparative, neoplastic and cancerous involved in reparation processes and in tumor growth. Cancer spheroids are different from neoplastic not only larger in size but also a tendency to merge, and high expression of p53. Expression of tumor markers p53, p16 and Ki-67 could be used in the early differential diagnosis of precancer and squamous cell carcinoma of the cervix.

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p53 / p16 / Ki-67 / cervical cancer / p53 / p16 / Ki-67 / HPV

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E A Kogan,Li Ts Ts,N M Faizullina,A V Kazachenko. EXPRESSION OF OCT-4, P53, P16 AND KI-67, WITH HPV ASSOCIATED PRECANCER AND CANCER OF THE CERVIX. Journal of Clinical Practice, 2016, 7(1): 34-38 DOI:10.17816/clinpract7134-38