MORPHOLOGICAL AND ULTRASOUND CHARACTERISTICS OF ENDOMETRIUM IN PATIENTS WITH BREAST CANCER AND THE RISK OF SECONDARY TUMORS
A V Gerasimov , S E Krasilnikov , A G Kedrova , N S Afonina , O E Nechaeva , T A Maksimenko , V V Kosyi
Journal of Clinical Practice ›› 2015, Vol. 6 ›› Issue (3) : 39 -47.
MORPHOLOGICAL AND ULTRASOUND CHARACTERISTICS OF ENDOMETRIUM IN PATIENTS WITH BREAST CANCER AND THE RISK OF SECONDARY TUMORS
The analysis of features of endometrial hyperplasia in patients with breast cancer (BC) receiving adjuvant tamoxifen therapy in the period from 2011 to 2014 inclusive. 196 patients with breast cancer with ultrasound criteria of endometrial hyperplasia were examined. A postoperative histopathologic examination revealed that the lesions were endometrial hyperplasias and with 4,1% malignant findings. Hyperplasia, polyps and endometrial cancer were diagnosed in patients receiving tamoxifen, which allowed a comparison clinicoanamnestic, ultrasound, morphological and genetic characteristics of the endometrium to recover a high risk of developing a second cancer, as well as offer a pathogenic variant of its prevention. The article can be interesting as for obstetrician-gynecologist, watching women after breast cancer treatment, and oncologists, choosing a drug for adjuvant therapy.
endometrium / Tamoxifen / breast cancer / estrogen receptor / endometrial hyperplasias
Gerasimov A.V., Krasilnikov S.E., Kedrova A.G., Afonina N.S., Nechaeva O.E., Maksimenko T.A., Kosyi V.V.
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