MORPHOMETRIC ASSESSMENT FOR THE PROGNOSIS OF CURRENT IN APLASTIC ANEMIA PATIENTS AFTER SPLENECTOMY

N S Fedorovskaya; D A Diakonov; N A Fedorovskaya; V N Pankov

doi:10.17816/clinpract5315-19

Journal of Clinical Practice ›› 2014, Vol. 5 ›› Issue (3) : 15 -19. DOI: 10.17816/clinpract5315-19

Articles

research-article

MORPHOMETRIC ASSESSMENT FOR THE PROGNOSIS OF CURRENT IN APLASTIC ANEMIA PATIENTS AFTER SPLENECTOMY

Author information +

History +

PDF

Abstract

The article presents the method of definition of the forecast of current in aplastic anemia patients after splenectomy, based on morphometric analysis of functional zones of a spleen in histologic cuts at painting by hematoxylin and eosine. At an estimation of a preparation in a light microscope by means of the computer program calculated the average area of a white pulp, further calculated its weight. Reduction in weight of a white pulp of a spleen below 10,0 g testifies to the favorable forecast of current aplastic anemia, increase - more than 10,0 g specifies adverse current of disease. This method is allows to solve differently the indications for immunosuppressive treatment of patients with given pathology after splenectomy.

Keywords

aplastic anemia / spleen / white pulp / morphometry

Cite this article

Download citation ▾

N S Fedorovskaya, D A Diakonov, N A Fedorovskaya, V N Pankov. MORPHOMETRIC ASSESSMENT FOR THE PROGNOSIS OF CURRENT IN APLASTIC ANEMIA PATIENTS AFTER SPLENECTOMY. Journal of Clinical Practice, 2014, 5(3): 15-19 DOI:10.17816/clinpract5315-19