PROMISING PHOTOSENSITIZER FOR ANTIMICROBIAL PHOTODYNAMIC THERAPY
M G Strakhovskaya , N S Belenikina , V V Nikitina , S Yu Kovalenko , I B Kovalenko , A V Averyanov , A B Rubin , T V Galochkina
Journal of Clinical Practice ›› 2013, Vol. 4 ›› Issue (1) : 25 -30.
PROMISING PHOTOSENSITIZER FOR ANTIMICROBIAL PHOTODYNAMIC THERAPY
A photosensitizer from polycationic metallophthalocyanines class is shown to have a high antimicrobial activity and a wide antimicrobial spectrum. It is established that the effective pho- todynamic inactivation of bacteria in the presence of photosensitizer of polycationic nature is determined by its electrostatic binding to negatively charged structures of bacterial cell walls. The usage of antimicrobial photodynamic therapy in medical practice is discussed from the point of view of the obtained results.
photosensitizer / reactive oxygen species / antimicrobial photodynamic therapy
Strakhovskaya M.G., Belenikina N.S., Nikitina V.V., Kovalenko S.Y., Kovalenko I.B., Averyanov A.V., Rubin A.B., Galochkina T.V.
/
| 〈 |
|
〉 |
PDF
