Generalized tetanus in an 11-year-old boy: A case report

Artem A. Kozlov , Irina V. Shevchuk , Aleksei E. Zavialov , Anatoly N. Emelyanov

Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care ›› 2021, Vol. 11 ›› Issue (1) : 69 -75.

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Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care ›› 2021, Vol. 11 ›› Issue (1) : 69 -75. DOI: 10.17816/psaic693
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Generalized tetanus in an 11-year-old boy: A case report

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Abstract

The study presents a case report of a generalized form of severe tetanus in an unvaccinated 11-year-old child. Pain and convulsive syndromes, respiratory failure, and damage to the gastrointestinal tract prevailed in the acute period. Antibiotic therapy, anti-tetanus serum, adequate pain relief, and anticonvulsant therapy were the leading treatments of the child. Moreover, the paper discusses literature data on the options for the clinical course and choice of treatment strategies. The lack of planned vaccination in children is unsafe.

Keywords

tetanus / clinical symptoms / therapy / children

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Artem A. Kozlov, Irina V. Shevchuk, Aleksei E. Zavialov, Anatoly N. Emelyanov. Generalized tetanus in an 11-year-old boy: A case report. Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care, 2021, 11(1): 69-75 DOI:10.17816/psaic693

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References

[1]

Filippov PG. Yushchuk ND, Vengerov YuYa. Infectious Diseases. National guidelines. Yushchuk ND, Vengerov YuYa., eds. Moscow: GEOTAR-Media; 2009. P. 521–529. (In Russ.)

[2]

Филиппов П.Г, Ющук Н.Д., Венгеров Ю.Я. Инфекционные болезни. Национальное руководство / под ред. Н.Д. Ющука, Ю.Я. Венгерова. М.: ГЭОТАР-Медиа, 2009. С. 521–529.

[3]

Maltseva LA, Mosentsev NF, Maltsev IA, Mishchenko EA. Tetanus: review of current guidelines on the epidemiology, etiology, pathogenesis, clinical picture, intensive care wartime and peacetime. Emergency Medicine. 2017;(3):86–90. DOI: 10.22141/2224-0586.3.82.2017.102329 (In Russ.)

[4]

Мальцева Л.А., Мосенцев Н.Ф., Мальцев И.А., Мищенко Е.А. Столбняк: обзор современных рекомендаций по эпидемиологии, этиологии, патогенезу, клинике, интенсивной терапии в период войн и в мирное время // Медицина неотложных состояний. 2017. № 3. С. 86–90. DOI: 10.22141/2224-0586.3.82.2017.102329

[5]

World Health Organization (WHO). Tetanus [Internet]. Available from: http://www.who.int/immunization/diseases/tetanus/en/

[6]

World Health Organization (WHO). Tetanus [Internet]. Режим доступа: http://www.who.int/immunization/diseases/tetanus/en/ Дата обращения: 31.03.21.

[7]

Yen LM, Thwaites CL. Tetanus. Lancet. 2019;393(10181):1657–1668. DOI: 10.1016/S0140-6736(18)33131-3

[8]

Yen L.M., Thwaites C.L. Tetanus // Lancet. 2019. Vol. 393, No. 10181. P. 1657–1668. DOI: 10.1016/S0140-6736(18)33131-3

[9]

European Centre for Disease Prevention and Control. Tetanus. In: ECDC. Annual epidemiological report for 2018. Stockholm: ECDC; 2020. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/Tetanus_AER_2018_Report.pdf

[10]

European Centre for Disease Prevention and Control. Tetanus. In: ECDC. Annual epidemiological report for 2018. Stockholm: ECDC; 2020. Режим доступа: https://www.ecdc.europa.eu/sites/default/files/documents/Tetanus_AER_2018_Report.pdf Дата обращения: 31.03.2021.

[11]

WHO vaccine-preventable diseases: monitoring system. 2020 global summary. Incidence time series for Russian Federation (RUS). Available from: https://apps.who.int/immunization_monitoring/globalsummary/incidences?c=RUS.

[12]

WHO vaccine-preventable diseases: monitoring system. 2020 global summary. Incidence time series for Russian Federation (RUS) Режим доступа: https://apps.who.int/immunization_monitoring/globalsummary/incidences?c=RUS. Дата обращения: 31.03.2021.

[13]

Petlakh VI. Tetanus in children: current concepts of the infection management. Almanac of Clinical Medicine. 2018;46(2):160–170. (In Russ.) DOI: 10.18786/2072-0505-2018-46-2-160-170

[14]

Петлах В.И. Столбняк у детей: современная концепция управления инфекцией // Альманах клинической медицины. 2018. Т. 46, № 2. С. 160–170. DOI: 10.18786/2072-0505-2018-46-2-160-170

[15]

Hatkar N, Shah N, Imran S, Jadhao A. Study of incidence, mortality & causes of neonatal tetanus among all Neonatal Intensive Care Unit [NICU] admissions in tertiary health care center of SBHGMC, Dhule. Journal of Evolution of Medical and Dental Sciences. 2015;4(40):6967–6973. DOI: 10.14260/jemds/2015/1012

[16]

Hatkar N., Shah N., Imran S., Jadhao A. Study of incidence, mortality & causes of neonatal tetanus among all Neonatal Intensive Care Unit [NICU] admissions in tertiary health care center of SBHGMC, Dhule // Journal of Evolution of Medical and Dental Sciences. 2015. Vol. 4, No. 40. P. 6967–6973. DOI: 10.14260/jemds/2015/1012

[17]

Simovanyan EM, Goncharova EL, Denisenko VB. Tetanus is a difficult diagnosis in children. Children’s Infections. 2019;18(4):70–72. (In Russ.) DOI: 10.22627/2072-8107-2019-18-4-70-72

[18]

Симованьян Э.М., Гончарова Е.Л., Денисенко В.Б. Трудности диагностики столбняка у детей // Детские инфекции. 2019. Т. 18, № 4. С. 70–72. DOI: 22627/2072-8107-2019-18-4-70-72

[19]

Kosam A, Durga K, Kumar H. Clinical profile and prognostic indicators of tetanus in children. Int J Med Res Rev. 2015;3(6):601–607. DOI:10.17511/ijmrr.2015.i6.117

[20]

Kosam A., Durga K., Kumar H. Clinical profile and prognostic indicators of tetanus in children // Int J Med Res Rev. 2015. Vol. 3, No. 6. P. 601–607. DOI:10.17511/ijmrr.2015.i6.117

[21]

Brook I. Tetanus in children. Pediatr Emerg Care. 2004;20(1):48–51. DOI: 10.1097/01.pec.0000106245.72265.71

[22]

Brook I. Tetanus in children // Pediatr Emerg Care. 2004. Vol. 20, No. 1. P. 48–51. DOI: 10.1097/01.pec.0000106245.72265.71

[23]

Naseem F, Mahar IA, Arif F. Two years’ study of Tetanus cases in a Paediatric Intensive Care Unit. Pak J Med Sci. 2016;32(3):641–645. DOI: 10.12669/pjms.323.9165

[24]

Naseem F., Mahar I.A., Arif F. Two years’ study of Tetanus cases in a Paediatric Intensive Care Unit // Pak J Med Sci. 2016. Vol. 32, No. 3. P. 641–645. DOI: 10.12669/pjms.323.9165

[25]

Dalal Sh, Samuelson Ju, Reed J, et al. Tetanus disease and deaths in men reveal need for vaccination. Bull World Health Organ. 2016;94(8):613–621. DOI: 10.2471/BLT.15.166777

[26]

Dalal Sh., Samuelson Ju., Reed J., et al. Tetanus disease and deaths in men reveal need for vaccination // Bull World Health Organ. 2016. Vol. 94, No. 8. P. 613–621. DOI: 10.2471/BLT.15.166777

[27]

Petlakh VI. Evolution of methods of treatment of tetanus in children (on the example of clinical case). Treatment and Prevention. 2017;7(4):63–66. (In Russ.)

[28]

Петлах В.И. Эволюция методов лечения столбняка у детей (на примере клинического наблюдения) // Лечение и профилактика. 2017. Т. 7, № 4. С. 63–66.

[29]

Jozani Z, Ahmad S, Agha S. Tetanus in an unvaccinated child: A case report. Asian Pacific Journal of Tropical Disease. 2012;2(4):335–336. DOI: 10.1016/S2222-1808(12)60073-5

[30]

Jozani Z., Ahmad S., Agha S. Tetanus in an unvaccinated child: A case report // Asian Pacific Journal of Tropical Disease. 2012. Vol. 2, No. 4. P. 335–336. DOI: 10.1016/S2222-1808(12)60073-5

[31]

Platonova TA, Golubkova AA, Koltunova ES, et al. National Vaccination Shedule: Quality of Performance and Determining Factors. Epidemiology and Vaccinal Prevention. 2019;18(2):97–103. (In Russ.) DOI: 10.31631/2073-3046-2019-18-2-97-103

[32]

Платонова Т.А., Голубкова А.А., Колтунова Е.С., и др. Национальный календарь профилактических прививок: качество исполнения и определяющие факторы // Эпидемиология и вакцинопрофилактика. 2019. Т. 18, № 2. С. 97–103. DOI: 10.31631/2073-3046-2019-18-2-97-103

[33]

Yeh FL, Dong M, Yao J, et al. SV2 mediates entry of tetanus neurotoxin into central neurons. PLoS Pathog. 2010;6(11):e1001207. DOI: 10.1371/journal.ppat.1001207

[34]

Yeh F.L., Dong M., Yao J., et al. SV2 mediates entry of tetanus neurotoxin into central neurons // PLoS Pathog. 2010. Vol. 6, No. 11. P. e1001207. DOI: 10.1371/journal.ppat.1001207

[35]

Hinfey PB, Ripper J, Engell KA, Chappell KN. Tetanus Treatment & Management. [Internet]. Available from: https://emedicine.medscape.com/article/229594-treatment

[36]

Hinfey PB, Ripper J, Engell KA, Chappell KN. Tetanus Treatment & Management. [Internet]. Режим доступа: https://emedicine.medscape.com/article/229594-treatment. Дата обращения: 31.03.21.

[37]

Rodrigo C, Fernando D, Rajapakse S. Pharmacological management of tetanus: an evidence-based review. Crit Care. 2014;18(2):217. DOI: 10.1186/cc13797

[38]

Rodrigo C., Fernando D., Rajapakse S. Pharmacological management of tetanus: an evidence-based review // Crit Care. 2014. Vol. 18, No. 2. P. 217. DOI: 10.1186/cc13797

[39]

Niu KY, Lin YK. Generalized tetanus. CMAJ. 2019;191(34):E944. DOI: 10.1503/cmaj.190161

[40]

Niu K.Y., Lin Y.K. Generalized tetanus // CMAJ. 2019. Vol. 191, No. 34. P. E944. DOI: 10.1503/cmaj.190161

[41]

Petlakh VI, Kuzmenko TN. Treatment of a child with generalized tetanus. Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care. 2017;7(2):51–54. (In Russ.)

[42]

Петлах В.И., Кузьменко Т.Н. Лечение ребенка с генерализованной формой столбняка // Российский вестник детской хирургии, анестезиологии и реаниматологии. 2017. Т. 7, № 2. С. 51–54.

[43]

World Health Organization (WHO). Prevention and management of wound infection [Internet]. Available from: https://www.who.int/hac/techguidance/tools/guidelines_prevention_and_management_wound_infection.pdf

[44]

World Health Organization (WHO). Prevention and management of wound infection [Internet]. Режим доступа: https://www.who.int/hac/techguidance/tools/guidelines_prevention_and_management_wound_infection.pdf Дата обращения: 31.03.2021.

[45]

Bush LM, Vazquez-Pertejo MT. Tetanus (Lockjaw) [Internet]. Available from: https://www.msdmanuals.com/professional/infectious-diseases/anaerobic-bacteria/tetanus

[46]

Bush L.M., Vazquez-Pertejo M.T. Tetanus (Lockjaw) [Internet]. Режим доступа: https://www.msdmanuals.com/professional/infectious-diseases/anaerobic-bacteria/tetanus. Дата обращения: 31.03.2021.

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Kozlov A.A., Shevchuk I.V., Zavialov A.E., Emelyanov A.N.

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