ETIOLOGY AND PATHOPHYSIOLOGY OF CHRONIC INTESTINAL PSEUDO-OBSTRUCTIVE SYNDROM IN CHILDREN. PART I. INTESTINAL MOTILITY PHYSIOLOGY
Yu. V. Averyanova , A. Yu. Razumovsky , A. E. Stepanov
Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care ›› 2016, Vol. 6 ›› Issue (1) : 82 -86.
ETIOLOGY AND PATHOPHYSIOLOGY OF CHRONIC INTESTINAL PSEUDO-OBSTRUCTIVE SYNDROM IN CHILDREN. PART I. INTESTINAL MOTILITY PHYSIOLOGY
Chronic intestinal pseudo-obstruction (CIPO) is a rare syndrome characterized by dilatation of the bowel lumen and abnormal motility in which no mechanical cause is identified. The syndrome appears at the background of congenital or acquired neuropathy, myopathy, or neuromyopathy. The article discusses the specifics of aetiopathogenesis of different disease forms, including de nova mutations discovered during the last decade. The article may be interested for surgeons who must be able to detect intestinal pseudo-obstruction to avoid unnecessary surgical interventions and also for other specialists who may encounter the syndrome in their practice.
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Averyanova Y.V., Razumovsky A.Y., Stepanov A.E.
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