Comparative assessment of the predictive ability of the nSOFA and NEOMOD scales in preterm newborns

Abstract

BACKGROUND: A life-threatening organ dysfunction is a strong predictor of in-hospital mortality and adverse outcomes in pediatric patients and full-term neonates. Predictors of outcomes of multiple-organ failure in preterm newborns have not yet been sufficiently determined.

AIM: To compare the discriminatory ability of neonatal sequential organ failure (nSOFA) and NEOMOD organ dysfunction scales as predictors of poor outcomes in very preterm newborns.

MATERIALS AND METHODS: This prospective observational study included 109 newborns with a birth weight of 1071 (772–1451) g and gestational age of 29 (26–32) weeks; 22 (20.4%) of them died.

RESULTS: The area under the receiver operating characteristic curve was 0.796 (95% confidence interval (CI) 0.763–0.827) for the nSOFA scale and 0.771 (95% CI 0.721–0.817) for the NEOMOD scale.

CONCLUSIONS. Both scales are suitable for measuring the severity of organ dysfunction in preterm newborns. nSOFA appears to predict mortality in preterm newborns.

Keywords

assessment of organ dysfunction / preterm newborns / intensive therapy

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