LATENT FORM OF CHRONIC HEPATITIS B

Abstract

Latent form of chronic hepatitis B can often occur in family practice. Only a complete clinical examination, using all the modern techniques, including immunohistochemistry, allows to identify the etiology of liver disease process pathology and to establish the correct diagnosis in patients with suspected chronic hepatitis

Keywords

latent form / chronic hepatitis B / immunohistochemistry

References

[1] Brechot С., Degos R., Lugassy С. et al. Hepatitis В DNA virus in patients with chronic liver disease and negative tests for hepatitis В surface antigen // N. Engi. J. Med. — 1985. —Vol. 312. — P. 270-276.

[2] Marusawa H., Uemoto S., Hijikata M. et al. Latent hepatitis В virus infection in healthy individuals with antibodies to hepatitis В core antigen // Hepatology. — 2000. — Vol. 31. — P. 488-495.

[3] Практические рекомендации Всемирной гастроэнтерологической организации. — 2008. — С. 39. — www.worldgastroenterology.org — Последнее посещение сайта 15.04.2013 г.

[4] Loriot M. A., Marcellin P., Bismuth E. et al. Demonstration of hepatitis В vims DNA by polymerase chain reaction in the serum and the liver after spontaneous or therapeutically induced HbeAg to anti-Hbe or HbsAg to anti-HBs seroconversion in patients with chronic hepatitis B // Hepatology. — 1992. — Vol. 15. — P. 32-36.

[5] Carman W. F. The clinical significance of surface antigen variants of hepatitis В virus // J. Viral. Hepatitis. — 1997. — Vol. 4 (Suppl). — P. 11-20.

[6] Chemin I., Zoulim F., Merle P. et al. High incidence of hepatitis В infections among chronic hepatitis cases of unknown etiology // J. Hepatology. — 2001. —Vol. 34. — № 3. — P. 447-54.

RIGHTS & PERMISSIONS

Kuznetsov N.I.