Anti-vegf therapy in treatment of vitreous hemorrhage due to proliferative diabetic retinopathy

Abstract

Purpose. To investigate the possibility of anti-VEGF therapy use in treatment of vitreous hemorrhage due to proliferative diabetic retinopathy without signs of vitreoretinal traction.

Materials and methods. In this case series study, 8 patients with severe vitreous hemorrhage due to proliferative diabetic retinopathy without signs of vitreoretinal traction were treated with intravitreal ranibizumab injections using treat-and-extend regimen. Patients were followed for 12–54 months.

Results. . Intravitreal ranibizumab injections using treat-and-extend regimen promoted a complete resolution of vitreous hemorrhage in one month after the 2^nd or the 3^rd monthly ranibizumab injection, followed by a significant visual acuity improvement.

Conclusion. Anti-VEGF therapy using treat-and-extend regimen could be recommended for treatment of vitreous hemorrhage due to proliferative diabetic retinopathy without signs of vitreoretinal traction.

Keywords

diabetic retinopathy / vitreous hemorrhage / VEGF

References

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RIGHTS & PERMISSIONS

Galimova A.B., Galimova V.U.