Experience of therapeutic eyelid hygiene products use in patients with anophthalmia after eyeball injury

Abstract

BACKGROUND: One of the purposes of ocular prosthetics is to prevent the progression of pathological processes in the eyelids and conjunctiva of the anophthalmic socket.

AIM: The aim of this study is to assess the effectiveness of therapeutic eyelid hygiene products: “Blepharowipe”, “Blepharogel cleansing” (Geltek-Medica, Russia), used in the late postoperative and long-term rehabilitation periods, in patients with anophthalmia who lost the eyeball as a result of an injury.

MATERIALS AND METHODS: For the study, 3 main (50 patients) and 3 corresponding control groups (50 patients) were created. The examination of patients included: complaints, medical history; biomicroscopy of the eyelids, the conjunctiva of the anophthalmic socket, and the surface of the ocular prosthesis. In the main groups, therapeutic eyelid hygiene products were used for 8 weeks in combination with regular ocular prosthesis care. In the control groups, eyelid hygiene products were not used. Assessment and analysis of the effectiveness of the products was carried out after 1, 2 and 4 weeks in group I and after 4 and 8 weeks in groups II and III based on the dynamics of patient complaints and objective examination indicators.

RESULTS: In the main groups I and II, there was a positive dynamics: normalization of the state of the eyelids and the conjunctiva of the anophthalmic socket; increasing comfort of an ocular prosthesis wear. In the main group III and in all control groups, no significant positive dynamics was noted.

CONCLUSIONS: The results of using the products included in the course of therapeutic hygiene of the eyelids: “Blepharowipe”, “Blepharogel cleansing” showed high efficiency, and give reason to recommend them in late postoperative and long-term rehabilitation periods in patients with anophthalmia.

Keywords

anophthalmia / ocular prosthesis / adaptation to an ocular prosthesis / “Blepharowipe” / “Blepharogel cleansing”

References

[1] Shif LV. Glaznoe protezirovanie. Moscow: Meditsina, 1981. 136 p. (In Russ.)

[2] Шиф Л.В. Глазное протезирование. Москва: Медицина, 1981. 136 с.

[3] Sadovskaya EP. Osobennosti glaznogo protezirovaniya v zavisimosti ot kliniko-anatomicheskikh kharakteristik anoftal’ma [dissertation]. Moscow, 2005. 206 p. (In Russ.)

[4] Садовская Е.П. Особенности глазного протезирования в зависимости от клинико-анатомических характеристик анофтальма: дис. … канд. мед. наук. Москва, 2005. 206 с.

[5] Shif LV. Udalenie glaza i voprosy kosmetiki. Moscow: Meditsina, 1973. 120 p. (In Russ.)

[6] Шиф Л.В. Удаление глаза и вопросы косметики. Москва: Медицина, 1973. 120 с.

[7] BenEzra D. Blepharitis and conjunctivitis. Guidelines for diagnosis and treatment. Editorial Glosa, 2006. 248 p.

[8] Jang SY, Lee SY, Yoon JS. Meibomian gland dysfunction in longstanding prosthetic eye wearers. Br J Ophthalmol. 2013;97:398–402. DOI: 10.1136/bjophthalmol-2012–302404

[9] Jang S.Y., Lee S.Y., Yoon J.S. Meibomian gland dysfunction in longstanding prosthetic eye wearers // Br J Ophthalmol. 2013. Vol. 97. P. 398–402. DOI: 10.1136/bjophthalmol-2012-302404

[10] Atin E, Meryem KU, Seyda KHG. Meibomian gland dysfunction and its association with ocular discomfort in patients with ocular prosthesis. Eye Contact Lens: Sci Clin Pract. 2020;46(5):285–290. DOI: 10.1097/ICL.0000000000000646

[11] Atin E., Meryem K.U., Seyda K.H.G. Meibomian gland dysfunction and its association with ocular discomfort in patients with ocular prosthesis // Eye Contact Lens: Sci Clin Pract. 2020. Vol. 46, No. 5. P. 285–290. DOI: 10.1097/ICL.0000000000000646

[12] Chiang C-C, Lin C-L, Tsai Y-Y, et al. Patients with blepharitis are at elevated risk of anxiety and depression. PLoS ONE. 2013;8(12): e83335. DOI: 10.1371/journal.pone.0083335

[13] Chiang C.-C., Lin C.-L., Tsai Y.-Y., et al. Patients with blepharitis are at elevated risk of anxiety and depression // PLoS ONE. 2013. Vol. 8, No. 12. ID e83335. DOI: 10.1371/journal.pone.0083335

[14] Kintyukhina NP. Rol’ kriteriev morfofunktsional’nogo sostoyaniya vek v diagnostike i otsenke ehffektivnosti lecheniya khronicheskikh blefaritov [dissertation]. Moscow, 2019. (In Russ.)

[15] Кинтюхина Н.П. Роль критериев морфофункционального состояния век в диагностике и оценке эффективности лечения хронических блефаритов: дис. … канд. мед. наук. Москва, 2019.

[16] Kim SE, Yoon JS, Lee SY. Tear measurement in prosthetic eye users with fourier-domain optical coherence tomography. Am J Ophtalmol. 2010;149(4):602–607. DOI: 10.1016/j.ajo.2009.10.023

[17] Kim S.E., Yoon J.S., Lee S.Y. Tear measurement in prosthetic eye users with fourier-domain optical coherence tomography // Am J Ophtalmol. 2010. Vol. 149, No. 4. P. 602–607. DOI: 10.1016/j.ajo.2009.10.023

[18] Trubilin VN, Poluninа EG, Kurenkov VV, et al. Therapeutic eyelids hygiene in the algorithms of prevention and treatment of ocular surface diseases. Part I. Ophthalmology in Russia. 2016;13(2):122–127. (In Russ.) DOI: 10.18008/1816-5095-2016-2-122-127

[19] Трубилин В.Н., Полунина Е.Г., Маркова Е.Ю., и др. Терапевтическая гигиена век в алгоритмах профилактики и лечения заболеваний глазной поверхности. Ч. 1 // Офтальмология. 2016. Т. 13, № 2. С. 122–127. DOI: 10.18008/1816-5095-2016-2-122-127

[20] Trubilin VN, Poluninа EG, Markova EY, et al. Therapeutic eyelids hygiene in the algorithms of prevention and treatment of ocular surface diseases. Part II. Ophthalmology in Russia. 2016;13(3):205–212. (In Russ.) DOI: 10.18008/1816-5095-2016-3-205-212

[21] Трубилин В.Н., Полунина Е.Г., Маркова Е.Ю., и др. Терапевтическая гигиена век в алгоритмах профилактики и лечения заболеваний глазной поверхности. Ч. 2 // Офтальмология. 2016. Т. 13, № 3. С. 205–212. DOI: 10.18008/1816-5095-2016-3-205-212

[22] Druyanova YuS. O primenenii plastmassovykh glaznykh protezov otechestvennogo proizvodstva. Oftal’mologicheskii zhurnal. 1984;(5):305–306. (In Russ.)

[23] Друянова Ю.С. О применении пластмассовых глазных протезов отечественного производства // Офтальмологический журнал. 1984. № 5. С. 305–306.

[24] Baranova NA, Senina IA, Nikolaenko VP. The influence of the locomotor stump’s form on the ocular prosthetics result with different methods of eye removal. Ophthalmology Reports. 2020;13(1):77–85. (In Russ.) DOI: 10.17816/OV13531

[25] Баранова Н.А., Сенина И.А., Николаенко В.П. Влияние формы опорно-двигательной культи на результат глазного протезирования при разных методах удаления глаза // Офтальмологические ведомости. 2020. Т. 13, № 1. С. 77–85. DOI: 10.17816/OV13531

[26] Davydov DV. Mediko-biologicheskie aspekty kompleksnogo ispol’zovaniya biomaterialov u patsientov s anoftal’mom [dissertation]. Moscow, 2000. (In Russ.)

[27] Давыдов Д.В. Медико-биологические аспекты комплексного использования биоматериалов у пациентов с анофтальмом: дис. … д-ра. мед. наук. Москва, 2000.

[28] Davydov DV, Baranova NA. Results of surgical treatment and rehabilitation of patients with post-traumatic subatrophy and anophthalmic syndrome in combination with bone deformities of the orbit. Ophthalmology Reports. 2022;15(4):15–26. (In Russ.) DOI: 10.17816/OV115061

[29] Давыдов Д.В., Баранова Н.А. Результаты хирургического лечения и реабилитации пациентов с посттравматической субатрофией и анофтальмическим синдромом в сочетании с костными деформациями глазницы // Офтальмологические ведомости. 2022. Т. 15, № 4. С. 15–26. DOI: 10.17816/OV115061

RIGHTS & PERMISSIONS

Eco-Vector