A comparative analysis of the course of wet age-related macular degeneration in eyes with incipient cataract and in eyes after phacoemulsification

Yuriy Sergeyevich Astakhov; Nikita Yur’yevich Dal’; Natal’ya Viktorovna Chistyakova

doi:10.17816/OV2014427-32

Ophthalmology Reports ›› 2014, Vol. 7 ›› Issue (4) : 27 -32. DOI: 10.17816/OV2014427-32

Articles

other

A comparative analysis of the course of wet age-related macular degeneration in eyes with incipient cataract and in eyes after phacoemulsification

Author information +

History +

PDF

Abstract

Many patients with wet age-related macular degeneration (AMD) also have a cataract in the same eye. Because there is a theoretical risk of progression of the degenerative processes in the macular area after surgical lens removal, this raises some ethical, clinical and economical questions for ophthalmologists. The purpose of the study was to compare the course of wet AMD in eyes with incipient cataract and the course in eyes after surgical cataract removal. Materials and methods: 135 eyes with wet AMD, 48 eyes - treated group - were subjects to phacoemulsification during the study, 87 eyes - control group - with incipient cataract without indications for surgery. Regular visits every 1.5 months during 2 years of follow-up with visual acuity testing, central retinal thickness analysis by optical coherence tomography (OCT). Anti-VEGF injections were performed according to a PRN regimen. Results: there was no statistically significant difference in visual acuity, central retinal thickness, intravitreal injection frequency between both groups during the study period. Conclusions: No influence of phacoemulsification on the wet AMD course was found.

Keywords

Cite this article

Download citation ▾

Yuriy Sergeyevich Astakhov, Nikita Yur’yevich Dal’, Natal’ya Viktorovna Chistyakova. A comparative analysis of the course of wet age-related macular degeneration in eyes with incipient cataract and in eyes after phacoemulsification. Ophthalmology Reports, 2014, 7(4): 27-32 DOI:10.17816/OV2014427-32

登录浏览全文

4963

注册一个新账户忘记密码

References

Publishing order | Descend order by publishing year | Descend order by cited within

[1]	Клинические рекомендации. Офтальмология (под ред. Л. К. Мошетовой, А. П. Нестерова, Е. А. Егорова Раздел: Возрастная макулярная дегенерация. Авторы раздела: Ю. С. Астахов, А. Б. Лисочкина, Ф. Е. Шадричев. М.: ГЭОТАР-Медиа. 2006; 164.

[2]	Armbrecht A. M., Findlay C., Kaushal S., Aspinall P., Hill A. R., Dhillon B. Is cataract surgery justified in patients with age related macular degeneration? - a visual function and quality of life assessment. Br J Ophthalmol. 2000; 84: 1343-1348.

[3]	Blair C. J., Ferguson J. Jr. Exacerbation of senile macular degeneration following cataract extraction. Am J Ophthalmol. 1979; 87: 77- 83.

[4]	Kaiserman I., Kaiserman N., Elhayany A., Vinker S. Cataract surgery is associated with a higher rate of photodynamic therapy for age-related macular degeneration. Ophthalmology. 2007; 114: 278-282.

[5]	Klein R., Klein B. E., Jensen S. C., Cruickshanks K. J. The relationship of ocular factors to the incidence and progression of age-related maculopathy. Arch Ophthalmol. 1998; 116: 506 -513.

[6]	Klein R., Klein B. E., Wong T. Y., Tomany S. C., Cruickshanks K. J. The association of cataract and cataract surgery with the long-term incidence of age-related maculopathy: the Beaver Dam eye study. Arch Ophthalmol. 2002; 120: 1551-1558.

[7]	Klein R., Klein B. E., Knudtson M. D., Meuer S. M., Swift M., Gangnon R. E. Fifteen-year cumulative incidence of age-related macular degeneration: the Beaver Dam Eye Study. Ophthalmology. 2007; 114: 253-262.

[8]	Livingston P. M., Carson C. A., Taylor H. R. The epidemiology of ca taract: a review of the literature. Ophthalmic. Epidemiol. 1995; 2: 151-164.

[9]	Lundqvist B., Monestam E. Longitudinal changes in subjective and objective visual function 5 years after cataract surgery: prospective population-based study. J Cataract Refract Surg. 2006; 32: 1944 -1950.

[10]	Lundstrom M., Brege K.G., Floren I., Lundh B., Stenevi U., Thorburn W. Cataract surgery and quality of life in patients with age related macular degeneration. Br J Ophthalmol. 2002; 86: 1330-1335. 1999; 25: 1492-1497.

[11]	Pollack A., Marcovich A., Bukelman A., Oliver M. Age-related macular degeneration after extracapsular cataract extraction with intraocular lens implantation. Ophthalmology. 1996; 103: 1546-1554.

[12]	Wang J. J., Klein R., Smith W., Klein B. E., Tomany S., Mit chell P. Cataract surgery and the 5-year incidence of late-stage agerelatedmaculopathy: pooled findings from the Beaver Dam and Blue Mountains eye studies. Ophthalmology. 2003; 110: 1960 -1967.

[13]	Wang J. J., Rochtchina E., Lee A. J. et al. Ten-year incidence and progression of age-related maculopathy: the blue Mountains EyeStudy. Ophthalmology. 2007; 114: 92-98.

[14]	Shuttleworth G. N., Luhishi E. A., Harrad R. A. Do patients with age related maculopathy and cataract benefit from cataract surgery? Br J Ophthalmol. 1998; 82: 611- 616.