Diagnostic perspectives and treatment efficacy in the Vogt-Koyanagi-Harada disease

Yuriy Sergeyevich Astakhov; Tatyana Igorevna Kuznetcova; Kirill Vladimirovich Khripun; Yanina Stanislavovna Konenkova; Yekaterina Vyacheslavovna Belozerova

doi:10.17816/OV2014384-92

Ophthalmology Reports ›› 2014, Vol. 7 ›› Issue (3) : 84 -92. DOI: 10.17816/OV2014384-92

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Diagnostic perspectives and treatment efficacy in the Vogt-Koyanagi-Harada disease

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Abstract

Vogt-Koyanagi-Harada (VKH) disease should be part of the differential diagnosis of a bilateral granulomatous uveitis. VKH is more common in the Mongoloid race (most frequently in Japanese, American Indians), and people of Hispanic descent. In Europeans, it is rare; mostly in women aged 30-50 with dark skin and hair pigmentation. The prodromal stage of VKH disease is non-specific but may include headache, vomiting and general malaise. Indocyanine green angiography may be helpful in making the diagnosis. Presenting a clinical case, the authors discuss the methods for diagnosis and follow-up for patients with Vogt-Koyanagi-Harada disease. Effective and timely treatment with high dose corticosteroids, if necessary in combination with immunosuppression, could save good visual functions.

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Vogt-Koyanagi-Harada (VKH) disease / uveitis / exudative retinal detachment / indocyanine green angiography (ICG)

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Yuriy Sergeyevich Astakhov, Tatyana Igorevna Kuznetcova, Kirill Vladimirovich Khripun, Yanina Stanislavovna Konenkova, Yekaterina Vyacheslavovna Belozerova. Diagnostic perspectives and treatment efficacy in the Vogt-Koyanagi-Harada disease. Ophthalmology Reports, 2014, 7(3): 84-92 DOI:10.17816/OV2014384-92

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