Cytomegalovirus uveitis in HIV-infected people: possible complications

Abstract

BACKGROUND: Cytomegalovirus uveitis is an AIDS-marker disease. If typical chorioretinal foci associated with cytomegalovirus viremia, inflammatory diseases of cytomegalovirus etiology of other organs are detected, etiotropic treatment and antiretroviral therapy are prescribed. Later on, the patient continues to be monitored by an ophthalmologist.

AIM: The aim is to identify the structure of complications, the frequency and the timing of their occurrence in cytomegalovirus uveitis in HIV-infected patients, the relationship with the treatment.

MATERIALS AND METHODS: The study was performed at the St. Petersburg Center for the Prevention and Control of AIDS and Infectious Diseases and the Department of Ophthalmology of the North-Western State Medical University named after I.I. Mechnikov. The study group consisted of 66 patients (97 eyes).

RESULTS: The development of complications of the disease was detected in 86.6% of patients. In patients, following complications were reported: retinal detachment, complicated cataract, partial optic nerve atrophy, cystoid macular edema, and secondary exotropia.

CONCLUSION: Cytomegalovirus uveitis in HIV-infected patients has a predominantly complicated course.

Keywords

cytomegalovirus uveitis / human immunodeficiency virus (HIV) / HIV-infection / opportunistic disease / immune reconstruction inflammatory diseases

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RIGHTS & PERMISSIONS

Sizova T., Khokkanen V., Zumbulidze N.