In this article the method of spinal-conduction anesthesia/analgesia, which was designed for knee joint replacement anesthesia, is described. Prospective observational research of 67 patients, who underwent the operation described above because of bone tumors, showed that this anesthesia method was effective in 100% of cases. During postoperative period failures of prolonged conductive anesthesia (15%, n = 10/67) were due to difficulties of perinerval catheters placement. Frequency of excessive hypotension during operation was 21% (n = 14/67), during postoperative period - 16% (n = 11/67).

Course of physiological labors of 120 patients with diabetes mellitus is researched. Patients were randomized into three groups depending on the anesthetic method. During labors central hemodynamic parameters, efficacy of analgesia, serum glucose level, patient and newborn status were assessed. It was shown, that the optimal method during physiological labor in patients with diabetes mellitus is naropin epidural analgesia, which stabilize serum glucose level, central hemodynamic parameters and relief pathological uterine contractions. If contraindications for epidural anesthesia exist, then perfalgan analgesia is the method of choice.