Ultrasound navigation during retrobulbar blockade in children with retinoblastoma and enucleation of the eyeball

Ekaterina I. Belousova , Nune V. Matinyan , Anastasia A. Tsintsadze , Leonid A. Martynov , Dmitry A. Kuznetsov , Ekaterina A. Kovaleva , Tatyana L. Ushakova , Vladimir G. Polyakov

Regional Anesthesia and Acute Pain Management ›› 2021, Vol. 15 ›› Issue (2) : 127 -136.

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Regional Anesthesia and Acute Pain Management ›› 2021, Vol. 15 ›› Issue (2) : 127 -136. DOI: 10.17816/RA90096
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Ultrasound navigation during retrobulbar blockade in children with retinoblastoma and enucleation of the eyeball

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Abstract

BACKGROUND: The retrobulbar block in children is used to enucleate analgesia in the intra- and postoperative period and prevent oculocardiac reflex (OCD), postoperative nausea, and vomiting. However, when the block is performed blindly, it results in serious complications.

AIM: This study aimed to evaluate the efficacy and safety of a retrobulbar block performed under ultrasound guidance compared with a retrobulbar block performed blindly during enucleation of the eyeball in children with retinoblastoma.

MATERIALS AND METHODS: A prospective randomized controlled trial was performed. The study included 40 patients who met the inclusion criteria. The patients were divided into two groups: 20 patients who underwent ultrasound-guided retrobulbar blockade (RBВ + ultrasound) and 20 patients who underwent blindly retrobulbar blockade (RBВ).

RESULTS: There was an insignificant decrease in intraoperative opioid requirements in the RBB + ultrasound group, where the average dose of fentanyl was 4±1.4 μg/kg, and in the RBB group, 4.7±0.8 μg/kg (p <0.05).

The time before the administration of the first dose of analgesic in the postoperative period was 4.7±0.8 h in the RBB group and 11.7±3.3 h in the RBB + ultrasound group (p <0.05). VAS and CHIPPS scores obtained 6 h after the end of surgery in the RBB + ultrasound and RBB groups were 1.8 (1.2; 2) and – 2.5 (3.8; 4.5) points (p <0.05), respectively.

CONCLUSION: There was no statistically significant difference between the time of the retrobulbar blockade under ultrasound guidance and the retrobulbar regional block performed blindly. Retrobulbar blockade performed under ultrasound guidance provides a decrease in intraoperative opioid requirements, stable intraoperative hemodynamics, and longer postoperative analgesia.

Keywords

сhildren / retinoblastoma / enucleation / ultrasound guidance / ropivacaine / retrobulbar block / oculocardial reflex

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Ekaterina I. Belousova, Nune V. Matinyan, Anastasia A. Tsintsadze, Leonid A. Martynov, Dmitry A. Kuznetsov, Ekaterina A. Kovaleva, Tatyana L. Ushakova, Vladimir G. Polyakov. Ultrasound navigation during retrobulbar blockade in children with retinoblastoma and enucleation of the eyeball. Regional Anesthesia and Acute Pain Management, 2021, 15(2): 127-136 DOI:10.17816/RA90096

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