Planning clinical research. Question #2: Choosing of endpoints
Galina P. Tikhova
Regional Anesthesia and Acute Pain Management ›› 2014, Vol. 8 ›› Issue (4) : 67 -70.
Planning clinical research. Question #2: Choosing of endpoints
The paper is devoted to the questions of correct choosing of endpoints that correspond the goal of the study as well as estimating of potential inaccuracy and bias of sample data due to particularities of different kind of endpoints. The author presents endpoints classification and considers various techniques to solve the problems arising from the endpoint nature.
protocol of clinical study / endpoint of clinical study
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Adams-Huet B., Ahn C. Bridging clinical investigators and statisticians: writing the statistical methodology for a research proposal. J Investig Med. 2009; 57(8): 818-824. |
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Prentice R.L. Surrogate endpoints in clinical trials: definition and operational criteria. Stat Med. 1989; 8(4): 431-440. |
Eco-Vector
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