Nefopam as a component of multimodal postoperative analgesia: the result in the group of patients undergone surgery for head and neck tumors in context of multicenter trial
V. V Balandin , Evgeniy S. Gorobets
Regional Anesthesia and Acute Pain Management ›› 2015, Vol. 9 ›› Issue (2) : 5 -8.
Nefopam as a component of multimodal postoperative analgesia: the result in the group of patients undergone surgery for head and neck tumors in context of multicenter trial
The goal of the study was to evaluate the affectivity of nefopam in postoperative pain management. Two hundred patients were enrolled into the prospective multicenter study on the base of 8 leading research centers of Russian Federation. The cohort includes 25 adult patients undergone surgery for head and neck tumors from Blokhin Russian Oncologic Research Center. All patient received analgesia for 3 postoperative days along the following scheme: nefopam 20mg i.v. 30 min before the end of the surgery, then every 8 hours combination of nefopam and NSAID. Visual- analogical 10-ball scale was used to evaluate analgesia. The results of the study suppose effectiveness and safety of nefopam as a component of postoperative multimodal analgesia.
nefopam / ketoprofene / multicenter study / multimodal postoperative analgesia / head and neck tumors
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