THE DEVELOPMENT OF THE RATIONAL SCHEME FOR THE APPLICATION OF DERINAT EYE DROPS, 0.25%, IN THE COMBINED TREATMENT OF EXPERIMENTAL OPHTHALMOHERPES

E. R Stirmanova; A. I Shchipanova; L. A Katargina

doi:10.17816/rpoj37486

Russian Pediatric Ophthalmology ›› 2012, Vol. 7 ›› Issue (2) : 46 -49. DOI: 10.17816/rpoj37486

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THE DEVELOPMENT OF THE RATIONAL SCHEME FOR THE APPLICATION OF DERINAT EYE DROPS, 0.25%, IN THE COMBINED TREATMENT OF EXPERIMENTAL OPHTHALMOHERPES

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Abstract

The authors report the results of the experimental evaluation of the efficacy of a new parmaceutical dosage form of derinat eye drops. The study was carried out using the experimental rabbit model of ophthalmoherpes. In the first series of experiments, the therapeutic efficacy of derinat eye drops, 0.25%, was compared with that of 3% zovirax eye ointment. It was shown that derinat produced a well-apparent therapeutic effect comparable with that of zovirax. The clinical efficacy of combined therapy with derinat and zovirax with different intervals between the applications of either preparation was estimated in the 2 nd and 3d series of experiments. It is concluded that it is important to strictly comply with the prescribed intervals (2 hours) between the applications of the tested medications.

Keywords

derinat eye drops / experimental investigations / herpetic keratitis

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E. R Stirmanova, A. I Shchipanova, L. A Katargina. THE DEVELOPMENT OF THE RATIONAL SCHEME FOR THE APPLICATION OF DERINAT EYE DROPS, 0.25%, IN THE COMBINED TREATMENT OF EXPERIMENTAL OPHTHALMOHERPES. Russian Pediatric Ophthalmology, 2012, 7(2): 46-49 DOI:10.17816/rpoj37486

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