Changes of properties of the mixed saliva and indicators of dental status in women with significant hypestrogenism

Abstract

The article examines the influence of the pronounced female estrogen deficiency appearing as a result of the surgically induced menopause on the indicators of mixed saliva and dental status during the first year after the surgical therapy. The following parameters were investigated: level of steroid and gonadotropic hormones, secretion rate, viscosity, pH level and ion composition of the mixed saliva, as well as indicators of oral hygiene, hard tooth tissues and periodontal status. There was performed a cytological and microbiological study of oral swabs, as well as the assessment of functional parameters of microcirculation in the oral mucosa. The results showed degradation of many quantitative and qualitative parameters of the mixed saliva and clinical and laboratory indicators of dental status, as well as negative changes of the microbial landscape and epithelium condition of the oral mucosa against the background of the acute estrogen deficiency.

Keywords

mixed saliva / hypestrogenism / surgical menopause

References

[1] Deepa T., Thirrunavukkarasu N. Saliva as a potential diagnostic tool. Indian J. Med. Scis. 2010; 64: 293-306.

[2] Вавилова Т.П., Янушевич О.О., Островская И.Г. Слюна. Аналитические возможности и перспективы. М.: Бином; 2014.

[3] Кисельникова Л.П., Попова Н.С. Стоматологический статус и профилактика стоматологических заболеваний у беременных. Институт Стоматологии. 2011; 50 (1): 86-7.

[4] Konttinen Y.T., Stegajev V., Al-Samadi A., Porola P., Hietanen J., Ainola M. Sjögren’s syndome and extragonadal sex steroid formation: A clue to a better disease control? J. Steroid Bioch. Mol. Biol. 2015; 145: 237-44.

[5] Meurman J.H., Tarkkila L., Tiitinen A. The menopause and oral health. Maturitas. 2009; 63 (1): 56-62.

[6] Tsinti M., Kassi E., Korkolopoulou P., Kapsogeorgou E., Moutsatsou P., Patsouris E. et al. Functional estrogen receptors alpha and beta are expressed in normal human salivary gland epithelium and apparently mediate immunomodulatory effects. Eur. J. Oral Sci. 2009; 117 (5): 498-505.

[7] Вавилова Т.П. Биохимия тканей и жидкостей полости рта. М.: ГЭОТАР - Медиа; 2008.

[8] Островский О.В., Храмов В.А., Попова Т.А. Биохимия полости рта. Волгоград: ВолГМУ; 2010.

RIGHTS & PERMISSIONS

Eco-Vector