ANTI-INFLAMMATORY EFFECT OF ASCORBATE CHITOSAN IN THE PERIODONTAL DISEASE TREATMENT

I. V Zudina; N. V Bulkina; P. V. Ivanov; A. P Vedyaeva; E. V Ivanova

doi:10.17816/dent.39131

Russian Journal of Dentistry ›› 2013, Vol. 17 ›› Issue (2) : 16 -19. DOI: 10.17816/dent.39131

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ANTI-INFLAMMATORY EFFECT OF ASCORBATE CHITOSAN IN THE PERIODONTAL DISEASE TREATMENT

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Abstract

It was studied the effect of the gum treatment with the gel-like form of the ascorbate chitosan on the dynamics of the changes in the level of cytokines (TNF-а, IL-1fi, IL-8 and IL-1ra) in the periodontal pockets liquidfrom patients who have the generalized type of the inflammation in the periodontal tissues. It was found that chitosan ascorbate exhibits a pronounced anti-inflammatory activity, probably, due to the regulation of the IL-1fi and TNF-а cytokine levels in the inflammatory focus.

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gingivitis / periodontitis / chitosan ascorbate / cytokines

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I. V Zudina, N. V Bulkina, P. V. Ivanov, A. P Vedyaeva, E. V Ivanova. ANTI-INFLAMMATORY EFFECT OF ASCORBATE CHITOSAN IN THE PERIODONTAL DISEASE TREATMENT. Russian Journal of Dentistry, 2013, 17(2): 16-19 DOI:10.17816/dent.39131

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