A study of soluble osteoclast-activating factor and osteoprotegerin in mixed saliva of patients with periodontitis
T P Vavilova , G S Pashkova , V M Grinin , T P Vavilova , G S Pashkova , V M Grinin
Russian Journal of Dentistry ›› 2010, Vol. 14 ›› Issue (2) : 11 -14.
A study of soluble osteoclast-activating factor and osteoprotegerin in mixed saliva of patients with periodontitis
Twenty-nine patients with chronic generalized periodontitis were studied. The quantity of the soluble receptor of the activator of nucleation of kappa B ligands (sRANKL) and osteoprotegerin as well as the activity of lactat-dehydrogenases, aspartataminotransferase, alaninaminotransferase, and alkaline phosphatase were measured before and after periodontological treatment with immune-enzyme method. The study found a reduction in sRANKL and the activity of the mentioned enzymes after the treatment, which evidenced stabilization of the inflammatory process and reduction in the intensity of the destructive process in periodontal bony tissue.
sRANKL / periodontitis / sRANKL / osteoprotegerin / saliva enzyme
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