Clinical case of surgical treatment of patient with toxic phosporus osteonecrosis of maxilla

Abstract

During the last few years on the territory of the Russian Federation, the number of cases of toxic phosphoric osteonecrosis of the jaws illicit use of drugs of “artisanal” production (pervitin, desomorphin). The aim of our study was to increase the effectiveness of surgical treatment of a patient diagnosed of toxic phosphorus necrosis of the maxilla. We performed a comprehensive treatment of a patient with a history of drug addiction and the above diagnosis. We performed complete resection of pathologically altered tissues and reconstructive techniques using local tissues and a replaced flap. This achieves good esthetic and functional results in the early and late postoperative period. Thus, we can use our proposed method of surgical treatment in similar clinical situations.

Keywords

toxic phosphorus osteonecrosis / maxilla / facial skull / drug addiction

References

[1] Adornato MC, Morcos I, Rozanski J. The treatment of bisphosphonate-associated osteonecrosis of the jaws with bone resection and autologous platelet-derived growth factors. J Am Dent Assoc. 2007;138(7):971–7. doi: 10.14219/jada.archive.2007.0294.

[2] Adornato M.C., Morcos I., Rozanski J. The treatment of bisphosphonate-associated osteonecrosis of the jaws with bone resection and autologous platelet-derived growth factors. J Am Dent Assoc. 2007;138(7):971–7. Doi: 10.14219/jada.archive.2007.0294.

[3] Basin EM, Medvedev YuA. Toxic phosphorus osteonecrosis of facial bones among drug addicts to desomorphine and pervitin. Part I. Stoma-tologiya. 2015;94(2):53–7. (in Russian) doi: 10.17116/stomat201594253–57.

[4] Басин Е.М., Медведев Ю.А. Токсические фосфорные остеонекрозы лицевого черепа у лиц с наркотической зависимостью от дезоморфина и первитина. Часть I. Стоматология. 2015;94(2):53–7. doi: 10.17116/stomat201594253–57.

[5] Marx RE, Sawatari Y, Fortin, M, Broumand V. Bisphosphonate induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recog-nition, prevention, and treatment. J Oral Maxillofac Surg. 2005;63(11):1567–75. doi: 10.1016/j.joms.2005.07.010.

[6] Marx, R. E., Sawatari, Y., Fortin, M., Broumand V. Bisphosphonate induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment. J Oral Maxillofac Surg. 2005;63(11):1567–75. doi: 10.1016/j.joms.2005.07.010.

[7] Coleman RE. Risks and benefits of bisphosphonates. Br J Cancer. 2008;98(11):1736–40. doi: 10.1038/sj.bjc.6604382.

[8] Coleman R.E. Risks and benefits of bisphosphonates. Br J Cancer. 2008;98(11):1736–40. doi: 10.1038/sj.bjc.6604382.

[9] Dimopoulos M, Kastritis E, Moulopoulos LA, Melakopoulos I, Anagnostopoulos A, Gika D. et al. The incidence of osteonecrosis of the jaw in pa-tients with multiple myeloma who receive bisphosphonates depends on the type of bisphosphonate. Blood. 2005;106(11):637. doi: 10.1182/blood.v106.11.637.637.

[10] Dimopoulos M., Kastritis E., Moulopoulos L.A., Melakopoulos I., Anagnostopoulos A., Gika D. et al. The incidence of osteonecrosis of the jaw in patients with multiple myeloma who receive bisphosphonates depends on the type of bisphosphonate. Blood. 2005;106(11):637. doi: 10.1182/blood.v106.11.637.637.

[11] Eisele DW, Smith RV. Complications in head and neck surgery. 2nd ed. Philadelphia: Mosby, Elseiver; 2009.

[12] Eisele D.W., Smith R.V. Complications in head and neck surgery. 2nd ed. Philadelphia: Mosby, Elseiver; 2009.

[13] Medvedev YuA, Basin EM, Serova NS, Korshunova AV, Babkova AA, Kureshova DN. Total jaw osteonecrosis among drug addicts. Rossiyskiy stoma-tologicheskiy zhurnal. 2016;20(4):183–9. (in Russian) doi: 10.18821/1728–28022016;20(4)183–189.

[14] Медведев Ю.А., Басин Е.М., Серова Н.С., Коршунова А.В., Бабкова А.А., Курешова Д.Н. Тотальные некрозы костей лицевого черепа у лиц с наркотической зависимостью. Российский стоматологический журнал. 2016;20(4):183–9. doi: 10.18821/1728–28022016;20(4)183–189.

[15] Malanchuk VA, Brodetskiy IS. Complex treatment of patients with osteomyelitis of the jaws on the background of drug addiction. Vestnik Vi-tebskogo gosudarstvennogo meditsinskogo universiteta. 2014;13(2):115–23. (in Russian)

[16] Маланчук В.А., Бродецкий И.С. Комплексное лечение больных остеомиелитом челюстей на фоне наркотической зависимости. Вестник Витебского государственного медицинского университета. 2014;13(2):115–23.

RIGHTS & PERMISSIONS

Eco-Vector