Common loss of the I-th three months gestation, observation tactics

Abstract

The common loss of gestation is a poly etiological complication during pregnancy time, where together with causes and factors of embryo/fetus peril there are destructions of the conjugal reproductive system. Main disturbances due to aborts in early terms are cariotype breakages: chromosome translocations and inversions were revealed in 8, 8% of inspected conjugal pairs, “cariotype peculiarities” in 72, 7%, conjugal compatibility according to HL А тогеЗ antigens was detected in 59, 3%. Disturbances of trophoblast invasion processes and placenta formation are evident because of hormonal distortions (NLF, hyperandrogeny), autoimmune distortions and chronicle endometritis with high level of anti-inflammatory cytokines. The development of placenta insufficiency in patients with these disturbances leads to pregnancy interruption.

Keywords

habitual pregnancy loss / polyetiologic complication of the course of pregnancy / miscarriage of the first trimester / reproductive system

References

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