Development conception of systemic inflammatory response on gestosis model

I. D. Medvinskiy , V. N. Serov , S. B. Tkachenko , L. N. Jurchenko , N. R. Shaburina-Basuk , A. D. Mazurov

Journal of obstetrics and women's diseases ›› 2002, Vol. 51 ›› Issue (1) : 33 -39.

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Journal of obstetrics and women's diseases ›› 2002, Vol. 51 ›› Issue (1) : 33 -39. DOI: 10.17816/JOWD89954
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Development conception of systemic inflammatory response on gestosis model

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In this work, the results are reported concerning studies of homeostasis in 719 patients-women with pathologically (gestosis) and physiologically continuing pregnancy in gestation dynamics and in 30 women without pregnancy. One analyzes namnestic, clinical and also 154 paraclinical indexes in the following systems: hematological, hemo coagulable, acute stage proteins, immune, endothelial, pro- and anti-oxidative, mother and fetus hemodynamics, gas homeostasis, functional detoxification system. The obtained data allowed consider the analogy between homeostasis change at gestosis and system inflammatory response syndrome (SIRS), form the functional development scheme SIRS during pregnancy with gestation stages verification. Comparing SIRS stages, which we put in estimation of the character of continuing pregnancy, with traditional gestosis criteria has permitted to classify the gestosis gravity degree tacking into account SIRS staginess.

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I. D. Medvinskiy, V. N. Serov, S. B. Tkachenko, L. N. Jurchenko, N. R. Shaburina-Basuk, A. D. Mazurov. Development conception of systemic inflammatory response on gestosis model. Journal of obstetrics and women's diseases, 2002, 51(1): 33-39 DOI:10.17816/JOWD89954

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