Fetal adrenal cortex function in pregnancy, complicated by maternal insulin-dependent diabetes mellitus

E. V. Shelaeva; A. V. Mikhailov; V. L. Borodina; T. I. Oparina

doi:10.17816/JOWD89530

Journal of obstetrics and women's diseases ›› 2001, Vol. 50 ›› Issue (2) : 80 -84. DOI: 10.17816/JOWD89530

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Fetal adrenal cortex function in pregnancy, complicated by maternal insulin-dependent diabetes mellitus

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Abstract

Fetal adrenal cortex glucocorticoid andfetal hypophysial adrenocorticotropic function in normal pregnancy and pregnancy, complicated with maternal insulin dependent diabetes mellitus were examined in the present study. Statistically significant feta l hypercortisolemia was observed in pregnancies, complicated by insulin-dependent diabetes mellitus. Correlations between vascular complications o f maternal insulin-dependent diabetes mellitus and fetal cortisol andACTG levels were revealed during the investigation. Severe vascular lesions o f maternal diabetes have been associated with delayed feta l lung maturity. Fetal pulmonary maturity was significantly associated with fe ta l cortisol levels.

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fetal adrenal cortex / adenohypophysis / hypercortisolism

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E. V. Shelaeva, A. V. Mikhailov, V. L. Borodina, T. I. Oparina. Fetal adrenal cortex function in pregnancy, complicated by maternal insulin-dependent diabetes mellitus. Journal of obstetrics and women's diseases, 2001, 50(2): 80-84 DOI:10.17816/JOWD89530

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References

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