Fetal adrenal cortex function in pregnancy, complicated by maternal insulin-dependent diabetes mellitus
E. V. Shelaeva , A. V. Mikhailov , V. L. Borodina , T. I. Oparina
Journal of obstetrics and women's diseases ›› 2001, Vol. 50 ›› Issue (2) : 80 -84.
Fetal adrenal cortex function in pregnancy, complicated by maternal insulin-dependent diabetes mellitus
Fetal adrenal cortex glucocorticoid andfetal hypophysial adrenocorticotropic function in normal pregnancy and pregnancy, complicated with maternal insulin dependent diabetes mellitus were examined in the present study. Statistically significant feta l hypercortisolemia was observed in pregnancies, complicated by insulin-dependent diabetes mellitus. Correlations between vascular complications o f maternal insulin-dependent diabetes mellitus and fetal cortisol andACTG levels were revealed during the investigation. Severe vascular lesions o f maternal diabetes have been associated with delayed feta l lung maturity. Fetal pulmonary maturity was significantly associated with fe ta l cortisol levels.
fetal adrenal cortex / adenohypophysis / hypercortisolism
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